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![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0208-1.jpg)
![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0208-2.jpg)
![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0208-3.jpg)
![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0208-4.jpg)
![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0208-5.jpg)
![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0208-6.jpg)
![SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)](/Public/upfile/pic/product/cell-line-new.jpg)
产品概述
| 名称 | SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确) |
| 别称 | SHSY5Y; SHSY-5Y; SH-Sy5y; SK-SH-SY5Y; SY5Y |
| 种属 | 人 |
| 生长特性 | 贴壁细胞，极少量悬浮 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：90%FBS+10%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 1.该细胞容易聚团，传代第二天轻微聚团甚至漂浮为正常现象，无需换液继续培养2~3天后细胞可正常贴壁；2.细胞聚团严重影响细胞生长后，可用胰酶消化细胞使之重新分散，传代后少动少换液，聚团会有改善。 |
| 背景描述 | SH-SY5Y细胞是于1970年建自骨瘤转移灶的神经母细胞瘤SK-N-SH细胞系经3次克隆后的亚系(SK-N-SH→SH-SY→SH-SY5→SH-SY5Y)。SH-SY5Y细胞显示中等水平的多巴胺-β-羟基酶活性，SH-SY5Y细胞的饱和密度大于1×10^6/cm^2。 |
| 年龄（性别） | 女性；4岁 |
| 组织来源 | 脑神经母细胞瘤，转移部位骨髓 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 神经母细胞瘤细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~48-72 hours |
| 抗原表达情况 | Blood Type A; Rh+ |
| 保藏机构 | ATCC; CRL-2266 DSMZ; ACC-209 ECACC; 94030304 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 17,19 D3S1358 15,16 D5S818 12 D7S820 7,10 D8S1179 15 D13S317 11 D16S539 8,13 D18S51 13,16 D19S433 13,14 D21S11 31,31.2 FGA 23.2,24 PentaD 10,12 PentaE 7,11 TH01 7,10 TPOX 8,11 vWA 14,18 D6S1043 12,18 D12S391 18,22 D2S441 11,11.3 -
STR鉴定图
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参考文献
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Exosome Heterogeneity Affects the Distal “Barrier-Crossing” Trafficking of Exosome Encapsulated Quantum Dots(2024/02/23)
作者：Di Wu, Hang Sun, Bingwei Yang
期刊：ACS Nano
影响因子 ：17.100
引用产品：CL-0208
-
An artificial protein modulator reprogramming neuronal protein functions(2024/03/06)
作者：Peihua Lin, Bo Zhang, Hongli Yang
期刊：Nature Communications
DOI：10.1038/s41467-024-46308-6
影响因子 ：16.600
引用产品：CL-0208
-
A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease(2024/01/24)
作者：Jiefei Wang, Shangguan Ping, Xiaoyu Chen
期刊：Nature Communications
DOI：10.1038/s41467-024-44737-x
影响因子 ：16.600
引用产品：CL-0208
-
Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides(2022/08/06)
作者：Zhanchi Zhu, Yuanxin Zhai, Ying Hao
期刊：Journal of Extracellular Vesicles
影响因子 ：16.000
-
SSK1-Loaded Neurotransmitter-Derived Nanoparticles for Alzheimers Disease Therapy via Clearance of Senescent Cells(2024/03/01)
作者：Wenbo Ji, Honglei Zhou, Wendanqi Liang
期刊：Small
影响因子 ：13.300
引用产品：CL-0208
-
Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease(2023/07/10)
作者：Xiansi Zeng, Wenshuo Geng, Yu Zhang
期刊：AGEING RESEARCH REVIEWS
影响因子 ：13.100
引用产品：CL-0208
-
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimers disease by enhancing autophagy(2021/01/01)
作者：Menglu Chen, Chungu Hong, Tao Yue
期刊：Theranostics
影响因子 ：12.400
引用产品：CL-0208
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Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury(2023/01/28)
作者：Yanhong Pei, Lifei Huang, Tong Wang
期刊：Materials Today Advances
DOI：10.1016/j.mtadv.2023.100349
影响因子 ：10.000
-
A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression(2024/02/27)
作者：Yongrui Hai, Renming Fan, Ting Zhao
期刊：PHARMACOLOGICAL RESEARCH
DOI：10.1016/j.phrs.2024.107115
影响因子 ：9.300
引用产品：CL-0208
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MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients(2023/03/16)
作者：Zhenggang Zhong, Jiabao Li, Jiayuan Zhong
期刊：npj Parkinsons Disease
DOI：10.1038/s41531-023-00479-z
影响因子 ：8.700
引用产品：CL-0208
-
Controllable mitochondrial aggregation and fusion by a programmable DNA binder(2023/07/06)
作者：Longyi Zhu, Yiting Shen, Shengyuan Deng
期刊：Chemical Science
影响因子 ：8.400
-
Modified acid polysaccharide derived from Salvia przewalskii with excellent wound healing and enhanced bioactivity(2024/01/30)
作者：Kui Zhao, Cheng Qian, Luming Qi
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.129803
影响因子 ：8.200
引用产品：CL-0208
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Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury(2024/04/26)
作者：Shikang Zhou, Ziqi Wang, Ting Wang
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155622
影响因子 ：7.900
引用产品：CL-0208
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NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells(2023/11/18)
作者：Caixia Zhang, Bo Jiao, Xueqin Cao
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.115889
影响因子 ：7.500
引用产品：CL-0208
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NIR-II light-activated two-photon squaric acid dye with Type I photodynamics for antitumor therapy(2022/10/24)
作者：Kexin Wang, Yunjian Xu, Zhenjiang Chen
期刊：Nanophotonics
影响因子 ：7.500
-
Nanosensor-Driven Detection of Neuron-Derived Exosomal Aβ42 with Graphene Electrolyte-Gated Transistor for Alzheimer’s Disease Diagnosis(2023/03/21)
作者：Jiahao Li, Wei Ni, Dan Jin
期刊：Analytical Chemistry
DOI：10.1021/acs.analchem.2c05751
影响因子 ：7.400
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Combined exposure to manganese and iron decreases oxidative stress-induced nerve damage by increasing Nrf2/HO-1/NQO1 expression(2023/12/20)
作者：Yuanyuan Fang, Mengjun Teng, Jianchao Peng
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115853
影响因子 ：6.800
引用产品：CL-0208
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Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring—Ca2+ overload via IP3R-GRP75-VDAC1 pathway(2024/03/15)
作者：Haoxuan Gao, Mi Tian, Xiaozhe Geng
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116218
影响因子 ：6.800
引用产品：CL-0208
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Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells(2022/12/09)
作者：CanCan Guo, Yi Lyu, ShuangShuang Xia
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2022.114350
影响因子 ：6.800
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LncRNA TUG1 compromised neuronal mitophagy in cerebral ischemia/reperfusion injury by targeting sirtuin 1(2022/03/28)
作者：LongXing Xue, SongFeng Chen, Shi-Xing Xue
期刊：Cell Biology And Toxicology
DOI：10.1007/s10565-022-09700-w
影响因子 ：6.100
引用产品：CL-0208
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Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson’s disease(2022/11/09)
作者：Haiyang Yu, Tong Sun, Zhen Wang
期刊：Neural Regeneration Research
影响因子 ：6.058
引用产品：CL-0208
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Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke(2022/12/19)
作者：Rong Zhou, Kuan Lin, Changlong Leng
期刊：Nutrients
影响因子 ：5.900
引用产品：CL-0208
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Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop(2022/04/04)
作者：Hengfang Tang, Zhiming Zheng, Han Wang
期刊：Nutrients
影响因子 ：5.900
引用产品：CL-0208
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RVG29 Peptide-Modified Exosomes Loaded with Mir-133b Mediate the RhoA-ROCK Pathway to Improve Motor and Neurological Symptoms in Parkinson’s Disease(2024/04/05)
作者：Peng Jiang, Yu Xiao, Xinmei Hu
期刊：ACS Biomaterials Science & Engineering
DOI：10.1021/acsbiomaterials.3c01622
影响因子 ：5.800
引用产品：CL-0208
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bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma(2022/09/27)
作者：Jingjing Song, Chao Ni, Xubin Dong
期刊：Frontiers in Oncology
影响因子 ：5.738
引用产品：CL-0208
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Chemical Hypoxia Induces Pyroptosis in Neuronal Cells by Caspase-Dependent Gasdermin Activation(2024/02/11)
作者：Chan Ho Park, Jun Young Park, Won Gil Cho
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0208
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The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model(2023/02/13)
作者：Ruru Jia, Yanling Liu, Ke Shuai
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0208
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α-Synuclein Induces Neuroinflammation Injury through the IL6ST-AS/STAT3/HIF-1α Axis(2023/01/11)
作者：Danyu Lin, Han Zhang, Jieli Zhang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
-
Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models(2024/03/17)
作者：Ruonan Wang, Shijia Kang, Zirui Zhao
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0208
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Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development(2024/03/01)
作者：Shuaiguang Li, Huarong Shao, Peixue Ling
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1366683
影响因子 ：5.600
引用产品：CL-0208
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HMGB3 is Associated With an Unfavorable Prognosis of Neuroblastoma and Promotes Tumor Progression by Mediating TPX2(2021/12/20)
作者：Xiaodan Zhong, Songling Zhang
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：5.500
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Huannao Yicong decoction ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by interfering with neurotoxic interaction of Aβ-tau(2023/08/01)
作者：Huiqin Zhang, Wenxuan Chen, Zehui Li
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0208
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Fabrication of P and N Co-Doped Carbon Dots for Fe3+ Detection in Serum and Lysosomal Tracking in Living Cells(2023/02/05)
作者：Yanzhi Xing, Mei Yang, Xuwei Chen
期刊：Biosensors-Basel
影响因子 ：5.400
-
Neurotoxicity study of ethyl acetate extract of Zanthoxylum armatum DC. on SH-SY5Y based on ROS mediated mitochondrial apoptosis pathway(2023/10/20)
作者：Jiafu Guo, Nannan Yang, Jian Zhang
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0208
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Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation(2024/04/13)
作者：Jiaxi Chen, Jieping Zhang, Lijuan Cai
期刊：Marine Drugs
影响因子 ：5.400
引用产品：CL-0208
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Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells(2022/08/17)
作者：Haiqun Dong, Shijing Liang, Yuling Xu
期刊：International Journal of Oncology
影响因子 ：5.200
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Novel flavonoid 1,3,4-oxadiazole derivatives ameliorate MPTP-induced Parkinsons disease via Nrf2/NF-κB signaling pathway(2023/06/03)
作者：Huawen Meng, Zhenbao Shen, Xianshe Meng
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2023.106654
影响因子 ：5.100
引用产品：CL-0208
-
Neuroprotective effect of chlorogenic acid on Parkinsons disease like symptoms through boosting the autophagy in zebrafish(2023/08/05)
作者：Xin Gao, Baoyue Zhang, Yuanteng Zheng
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2023.175950
影响因子 ：5.000
引用产品：CL-0208
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Novel Deoxyvasicinone–Donepezil Hybrids as Potential Multitarget Drug Candidates for Alzheimer’s Disease(2019/02/05)
作者：Hongtao Du, Xinlian Liu, Jusen Xie
期刊：ACS Chemical Neuroscience
DOI：10.1021/acschemneuro.8b00699
影响因子 ：5.000
-
Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis(2022/02/25)
作者：Jian Zhang, Wei Liu, Ping Ji
期刊：Bioengineered
DOI：10.1080/21655979.2022.2042999
影响因子 ：4.900
-
Effects of miRNAs in exosomes derived from α-synuclein overexpressing SH-SY5Y cells on autophagy and inflammation of microglia(2021/10/27)
作者：Tianen Zhou, Meng Zhang, Yingyu Xie
期刊：Cellular Signalling
DOI：10.1016/j.cellsig.2021.110179
影响因子 ：4.800
引用产品：CL-0208
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CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma(2022/02/15)
作者：Lin Qiu, Rui Zhou, Ziyan Luo
期刊：Frontiers in Oncology
影响因子 ：4.700
-
Libertellenone C attenuates oxidative stress and neuroinflammation with the capacity of NLRP3 inhibition(2024/02/26)
作者：Jie Cao, Lanqin Li, Runge Zhang
期刊：Natural Products and Bioprospecting
DOI：10.1007/s13659-024-00438-y
影响因子 ：4.700
引用产品：CL-0208
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Identifying the potential genes in alpha synuclein driving ferroptosis of Parkinson’s disease(2023/10/06)
作者：Min Wang, Taole Li, Rong Gao
期刊：Scientific Reports
DOI：10.1038/s41598-023-44124-4
影响因子 ：4.600
引用产品：CL-0208
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VCAM-1+ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis(2023/06/19)
作者：Xiao Zhang, Xiaoyu Sang, Yanting Chen
期刊：NEUROCHEMICAL RESEARCH
DOI：10.1007/s11064-023-03968-y
影响因子 ：4.400
-
The protective effects of Agomelatine against Aβ1-42 oligomers-induced cellular senescence mediated by SIRT6 and Agomelatine’s potential in AD treatment(2021/09/17)
作者：Jian Wang, Bo Zheng, Shu Yang
期刊：Human Cell
DOI：10.1007/s13577-021-00611-2
影响因子 ：4.374
引用产品：CL-0208
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Potential Cause-and-Effect Relationship between Gut Microbiota and Childhood Neuroblastoma: A Mendelian Randomization Analysis(2024/03/27)
作者：Jing Chu
期刊：INDIAN JOURNAL OF PEDIATRICS
DOI：10.1007/s12098-024-05065-6
影响因子 ：4.300
引用产品：CL-0208
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STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway(2024/02/08)
作者：XiaoLei Zhang, Yu Wang, Jia Lv
期刊：NEUROCHEMISTRY INTERNATIONAL
DOI：10.1016/j.neuint.2024.105683
影响因子 ：4.200
引用产品：CL-0208
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Exploring the Therapeutic Effects of Multifunctional N-Salicylic Acid Tryptamine Derivative against Parkinson’s Disease(2023/07/28)
作者：Xuelin Li, Shuzhi Wang, Shan Duan
期刊：ACS Omega
影响因子 ：4.100
-
EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells(2023/02/07)
作者：Yuwei Liu, Li Peng, Jing Chen
期刊：BMC Geriatrics
DOI：10.1186/s12877-023-03793-6
影响因子 ：4.100
引用产品：CL-0208
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S1PR2 Regulates Autophagy Through the AKT/mTOR Pathway to Promote Pathological Damage in Alzheimer’s Disease(2023/11/22)
作者：Xiaoping Wang, Rui Huang, Bin Huang
期刊：JOURNAL OF ALZHEIMERS DISEASE
影响因子 ：4.000
引用产品：CL-0208
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Inhibition of Astrocytic Carbohydrate Sulfotransferase 15 Promotes Nerve Repair After Spinal Cord Injury via Mitigation of CSPG Mediated Axonal Inhibition(2023/03/13)
作者：Liming Li, Heping Zheng, Xuepei Ma
期刊：Cellular And Molecular Neurobiology
DOI：10.1007/s10571-023-01333-9
影响因子 ：4.000
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miR-146a aggravates cognitive impairment and Alzheimer disease-like pathology by triggering oxidative stress through MAPK signaling(2021/3/11)
作者：Zhanqiang H., Haihua Q., Chi Z.
期刊：Neurologia
影响因子 ：3.900
引用产品：CL-0208
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α-synuclein accumulation in SH-SY5Y cell impairs autophagy in microglia by exosomes overloading miR-19a-3p(2019/01/24)
作者：Tianen Zhou, Danyu Lin, Ying Chen
期刊：EPIGENOMICS
影响因子 ：3.800
引用产品：CL-0208
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The neuroprotective effects of Insulin-Like Growth Factor 1 via the Hippo/YAP signaling pathway are mediated by the PI3K/AKT cascade following cerebral ischemia/reperfusion injury(2021/10/28)
作者：Pian Gong, Yichun Zou, Wei Zhang
期刊：Brain Research Bulletin
DOI：10.1016/j.brainresbull.2021.10.017
影响因子 ：3.715
引用产品：CL-0208
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Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy(2023/09/09)
作者：Yuanxin Huang, Sihui Lu, Yu Chen
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-023-02697-x
影响因子 ：3.600
引用产品：CL-0208
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Antitumor effect of Escherichia coli-derived outer membrane vesicles on neuroblastoma in vitro and in vivo : Effect of E. coli-OMVs on neuroblastoma(2022/09/20)
作者：Liming Jin, Zhaoxia Zhang, Xiaojun Tan
期刊：ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影响因子 ：3.511
引用产品：CL-0208
-
Energy metabolism disorders and oxidative stress in the SH-SY5Y cells following PM2.5 air pollution exposure(2022/08/23)
作者：Zhaofei Li, Fengjie Tian, Hongfang Ban
期刊：Toxicology Letters
DOI：10.1016/j.toxlet.2022.08.008
影响因子 ：3.500
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Insufficient autophagy enables the nuclear factor erythroid 2-related factor 2 (NRF2) to promote ferroptosis in morphine-treated SH-SY5Y cells(2023/12/05)
作者：Xin Huang, Xinyue Yan, Gang Chen
期刊：PSYCHOPHARMACOLOGY
DOI：10.1007/s00213-023-06485-6
影响因子 ：3.400
引用产品：CL-0208
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Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation(2024/01/30)
作者：Kaikai Zhou, Shasha Xu
期刊：PSYCHOPHARMACOLOGY
DOI：10.1007/s00213-024-06536-6
影响因子 ：3.400
引用产品：CL-0208
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Comparing the Impact of NIR, Visible and UV Light on ROS Upregulation via Photoacceptors of Mitochondrial Complexes in Normal, Immune and Cancer Cells(2023/01/01)
作者：Iuliia Golovynska, Sergii Golovynskyi, Junle Qu
期刊：PHOTOCHEMISTRY AND PHOTOBIOLOGY
影响因子 ：3.300
引用产品：CL-0208
-
The Co-oligomers of Aβ42 and Human Islet Amyloid Polypeptide Exacerbate Neurotoxicity and Alzheimer-like Pathology at Cellular Level(2024/04/09)
作者：Jiajun Deng, Bin Liu, Qian Tao
期刊：NEUROSCIENCE
DOI：10.1016/j.neuroscience.2024.04.002
影响因子 ：3.300
引用产品：CL-0208
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MiR‐370 accelerated cerebral ischemia reperfusion injury via targeting SIRT6 and regulating Nrf2/ARE signal pathway(2020/04/20)
作者：Zhongfan Ruan, Ming Xie, Shujia Gui
期刊：Kaohsiung Journal Of Medical Sciences
影响因子 ：3.300
引用产品：CL-0208
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Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome(2022/09/16)
作者：Guoqing Sun, Rui Zhang, Chengxiao Liu
期刊：Brain Sciences
影响因子 ：3.300
引用产品：CL-0208
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miR-15b-5p transcription mediated by CREB1 protects against inflammation and apoptosis in Parkinson disease models by inhibiting AXIN2 and activating Wnt/β-catenin(2023/11/07)
作者：Tianyi Liu, Guozhong Li
期刊：JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
影响因子 ：3.200
引用产品：CL-0208
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Midazolam alleviates cellular senescence in SH-SY5Y neuronal cells in Alzheimers disease(2022/11/28)
作者：Ping Wang, Peipei Wang, Hengfei Luan, Yong Wu, Ying Chen
期刊：Brain and Behavior
影响因子 ：3.100
引用产品：CL-0208
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METTL3 relieved the injury of SH-SY5Y cells treated with lipopolysaccharide and exposed to sevoflurane through regulating the m6A levels of Sox2(2023/03/28)
作者：Yilong Wang, Zeyong Yang
期刊：Brain and Behavior
影响因子 ：3.100
引用产品：CL-0208
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Sinigrin improves cerebral ischaemia-reperfusion injury by inhibiting the TLR4 pathway-mediated oxidative stress(2024/02/18)
作者：Shenglong Guo, Qi Lei, Qian Yang
期刊：Chemical Biology & Drug Design
影响因子 ：3.000
引用产品：CL-0208
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Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism(2023/09/16)
作者：Xinyu Wang, Chao Yan, Chaoyun Wang
期刊：BRAIN RESEARCH
DOI：10.1016/j.brainres.2023.148585
影响因子 ：2.900
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MiR‐29c protects against inflammation and apoptosis in Parkinsons disease model in vivo and in vitro by targeting SP1(2019/12/15)
作者：Ruili Wang, Ying Yang, Hui Wang
期刊：Clinical And Experimental Pharmacology And Physiology
影响因子 ：2.900
引用产品：CL-0208
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β-Elemene Improves Morphine Tolerance in Bone Cancer Pain via N-Methyl-D-Aspartate Receptor 2B Subunit-Mediated μ-Opioid Receptor(2022/09/17)
作者：Qinfei Zhou, Liyan Gong, Guanai Bao
期刊：Computational and Mathematical Methods in Medicine
影响因子 ：2.809
引用产品：CL-0208
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Silencing of purinergic receptor P2Y2 inhibited enteric neural crest cell proliferation, invasion and migration via suppressing ERK signaling pathway in Hirschsprung disease(2023/08/23)
作者：Dengrui Liu, Hongxia Kang, Mingtai Gao
期刊：3 Biotech
DOI：10.1007/s13205-023-03721-w
影响因子 ：2.800
引用产品：CL-0208
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Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment(2021/12/04)
作者：Changhong Tan, Xi Liu, Xiaoshuai Zhang
期刊：BMC Molecular and Cell Biology
DOI：10.1186/s12860-021-00398-y
影响因子 ：2.800
引用产品：CL-0208
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Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines(2023/04/12)
作者：Bo Jiao, Mi Zhang, Caixia Zhang
期刊：PeerJ
影响因子 ：2.700
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miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress(2019/09/07)
作者：Lumei Chi, Dan Jiao, Guangxian Nan
期刊：Acta Histochemica
DOI：10.1016/j.acthis.2019.08.005
影响因子 ：2.500
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Sevoflurane suppresses ALG13 transcription in a CREBBP-dependent manner to induce hippocampal damage and cognitive impairment(2023/10/30)
作者：Xiuping Gong, Qi Li, Yang Liu
期刊：NEUROSCIENCE LETTERS
DOI：10.1016/j.neulet.2023.137543
影响因子 ：2.500
引用产品：CL-0208
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Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance(2022/12/01)
作者：Yi Lyu, Xueke Ren, Cancan Guo
期刊：JOURNAL OF TOXICOLOGICAL SCIENCES
影响因子 ：2.000
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Benzo(a)pyrene-induced mitochondrial respiration and glycolysis disturbance in human neuroblastoma cells(2023/02/01)
作者：Yi Lyu, Jin Yang, LiXia Cheng
期刊：JOURNAL OF TOXICOLOGICAL SCIENCES
影响因子 ：2.000
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The Diagnostic Model of Ligusticum Chuanxiong Hort. Against Cerebral Stroke Using Network Pharmacology and Transcriptomics Analyses(2023/10/23)
作者：Jinfeng Zhang, Chongyin Cai, Ying Luo
期刊：Journal of Integrative Neuroscience
影响因子 ：1.800
引用产品：CL-0208
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