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产品概述
名称 | LN229 [LN-229; LNT-229] (人胶质母细胞瘤细胞) (STR鉴定正确) |
别称 | LN 229; LN229; LNT-229 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:5 |
推荐换液频率 | 2-3次/周 |
背景描述 | The LN-229 cell line was Established in 1979 from cells taken from a patient with right frontal parieto-occipital glioblastoma [PubMed. 10416987]. |
年龄(性别) | 女性;60岁 |
组织来源 | 大脑/右额叶顶枕叶皮质 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胶质母细胞瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~31 hours |
致瘤性 | Yes, forms tumors in nude mice. |
保藏机构 | ATCC; CRL-2611 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 19,20 D3S1358 16,17 D5S818 11,12 D7S820 8,11 D8S1179 13,14 D13S317 10,11 D16S539 12 D18S51 13,15 D19S433 12,17.2 D21S11 29,30 FGA 23 PentaD 10,11 PentaE 7,16 TH01 9.3 TPOX 8 vWA 16,19 D6S1043 11 D12S391 20,22 D2S441 10,11 -
STR鉴定图
参考文献
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Super-enhancer-driven LIF promotes the mesenchymal transition in glioblastoma by activating ITGB2 signaling feedback in microglia(2024/03/30)
作者:Han Xie, Yanyi Jiang, Yufei Xiang
期刊:NEURO-ONCOLOGY
影响因子 :15.900
引用产品:CL-0578
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SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma(2022/12/24)
作者:Liying Han, Jinpeng Zhou, Leiyang Li
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-05526-w
影响因子 :9.000
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Multi-omics analysis reveals the involvement of origin recognition complex subunit 6 in tumor immune regulation and malignant progression(2023/10/12)
作者:Jinfeng Zhu, Qitong Chen, Liyun Zeng
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1236806
影响因子 :7.300
引用产品:CL-0578
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Hsa_circ_0021205 enhances lipolysis via regulating miR-195-5p/HSL axis and drives malignant progression of glioblastoma(2024/02/10)
作者:Suwen Li, Jiaqi Yuan, Zhe Cheng
期刊:Cell Death Discovery
DOI:10.1038/s41420-024-01841-7
影响因子 :7.000
引用产品:CL-0578
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Immune cell infiltration and drug response in glioblastoma multiforme: insights from oxidative stress-related genes(2024/04/02)
作者:Kan Wang, Yifei Xiao, Ruipeng Zheng
期刊:Cancer Cell International
DOI:10.1186/s12935-024-03316-2
影响因子 :5.800
引用产品:CL-0578
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Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients(2021/05/29)
作者:Zhendong Liu, Wang Zhang, Xingbo Cheng
期刊:Molecular Medicine
DOI:10.1186/s10020-021-00316-0
影响因子 :5.700
-
Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity(2023/03/14)
作者:Xinzhuang Wang, Junyi Ye, Ming Gao
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.109987
影响因子 :5.600
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A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response(2023/10/18)
作者:Wei-Wei Duan, Li-Ting Yang, Jian Liu
期刊:CNS Neuroscience & Therapeutics
影响因子 :5.500
引用产品:CL-0578
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Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma(2024/04/11)
作者:Zhen Liu, Liangwang Yang, Wenqi Wu
期刊:Frontiers in Cell and Developmental Biology
DOI:10.3389/fcell.2024.1375030
影响因子 :5.500
引用产品:CL-0578
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)
作者:Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong
期刊:CNS Neuroscience & Therapeutics
影响因子 :5.500
引用产品:CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122
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A novel immunogenic cell death-related gene risk signature can identify biomarkers of gliomas and predict the immunotherapeutic response(2024/01/15)
作者:Xuewu Tang, Kan Wang, Jinchao Yang
期刊:American Journal of Cancer Research
DOI:PMID:38323285
影响因子 :5.300
引用产品:CL-0578
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A novel necroptosis-related gene signature for predict prognosis of glioma based on single-cell and bulk RNA sequencing.(2022/08/30)
作者:Kai Guo, Xinxin Duan, Jiahui Zhao
期刊:Frontiers in Molecular Biosciences
影响因子 :5.000
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Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis(2021/8/31)
作者:Xian Bao, Yibo Peng, Jun Shen
期刊:Bioengineered
DOI:10.1080/21655979.2021.1976712
影响因子 :4.900
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Knockdown of long non-coding RNA AGAP2-AS1 suppresses the proliferation and metastasis of glioma by targeting microRNA-497-5p(2021/10/28)
作者:Yi Sun, Yulong Shen, Xing Li
期刊:Bioengineered
DOI:10.1080/21655979.2021.1995573
影响因子 :4.900
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The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells(2021/11/18)
作者:Dong Xuchen, Zhang Peng, Liu Liang
期刊:Frontiers in Oncology
影响因子 :4.700
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Zinc finger and SCAN domain-containing 18 suppresses the proliferation, self-renewal, and drug resistance of glioblastoma cells(2023/06/03)
作者:Yan Wang, Jingwei Peng, Chenchen Song
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e17000
影响因子 :4.000
引用产品:CL-0578
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Phospholipid scramblase 1 acts through the IL-6/JAK/STAT3 pathway to promote the malignant progression of glioma(2024/04/16)
作者:ShiZhen Zhou, Jun Xu, YuFang Zhu
期刊:ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影响因子 :3.900
引用产品:CL-0578
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CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis(2021/10/09)
作者:Rongcai Liu, Weimin Dai, An Wu
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08803-7
影响因子 :3.800
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Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281(2022/01/04)
作者:Jun Wang, Juan Li, Peng Duan
期刊:Neurotoxicity Research
DOI:10.1007/s12640-021-00464-5
影响因子 :3.700
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Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway(2024/03/28)
作者:Chao Zhang, Qian Peng, Yuhang Tang
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-024-05625-5
影响因子 :3.600
引用产品:CL-0578
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Propofol inhibits glioma progression by regulating circMAPK4/miR-622/HOXA9 axis(2022/11/03)
作者:Xiao, Gaopeng, Yu, Liuqiong, Tan, Wenmin, Yang, Hao, Li, Wensen, Xia, Rongzhou, Li, Yujin
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01099-x
影响因子 :3.600
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CircTTBK2 Contributes to the Progression of Glioma Through Regulating miR-145-5p/CPEB4 Axis(2020/9/8)
作者:Yan Liu, Ruilong Li, Xuan Wang
期刊:Cancer Management and Research
影响因子 :3.300
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VSIG4 Silencing Inhibits Glioblastoma Growth by Regulating the JAK2/STAT3 Pathway(2023/06/02)
作者:Congying Zheng, Chengliang Mao, Kai Tang
期刊:Neuropsychiatric Disease and Treatment
影响因子 :3.200
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HNF4G accelerates glioma progression by facilitating NRP1 transcription(2023/02/01)
作者:Hongmin Che, Qi Zheng, Zijun Liao
期刊:Oncology Letters
影响因子 :2.900
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