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产品概述
名称 | U-118 MG (人脑星形胶质母细胞瘤) (STR鉴定正确) |
别称 | U-118 MG; U-118-MG; U118-MG; U118MG; U118; 118 MG; 118MG |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 混合形 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | 注意:据报道来自不同个体的胶质母细胞瘤细胞株U-118 MG(HTB-15)和U-138 MG(HTB-16)有着一致的VNTR和相近的STR模式。U-118 MG(HTB-15)和U-138 MG(HTB-16)细胞遗传学上很相似并有至少六个衍生标记染色体。这是1966-1969年间J·Ponten和其同事从恶性神经胶质瘤中构建的细胞株中的一株(其它包括HTB-14、HTB-16和HTB-17)。1987年,用BM-Cycline培养6周去除了U-118 MG(HTB-15)细胞支原体污染。 |
年龄(性别) | 男性;50岁 |
组织来源 | 器官:大脑;肿瘤阶段:按2007年的标准归为IV期;疾病:星形胶质母细胞瘤 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胶质瘤细胞 |
生物安全等级 | BSL-1 |
保藏机构 | ATCC; HTB-15 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 11,12 D2S1338 23,25 D3S1358 15 D5S818 11 D7S820 9 D8S1179 14,15 D13S317 9 D16S539 12,13 D18S51 13 D19S433 13 D21S11 27,32.2 FGA 23 PentaD 10,13 PentaE 7 TH01 6 TPOX 8 vWA 18 D6S1043 12 D12S391 19,22 D2S441 11,15 -
STR鉴定图
参考文献
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Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming.(2022/10/03)
作者:Ting Zhao, Jianming Zeng, Yujie Xu
期刊:Theranostics
影响因子 :12.400
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)
作者:Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong
期刊:CNS Neuroscience & Therapeutics
影响因子 :5.500
引用产品:CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122
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A systematic framework for identifying prognostic necroptosis-related lncRNAs and verification of lncRNA CRNDE/miR-23b-3p/IDH1 regulatory axis in glioma(2023/11/06)
作者:Yangxia Chen, Di Hu, Fang Wang
期刊:Aging-US
影响因子 :5.200
引用产品:CL-0458
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DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression(2024/03/21)
作者:Youlin Chen, Yi Liu, Yan Xu
期刊:World Journal of Oncology
影响因子 :5.200
引用产品:CL-0458
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Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway(2023/06/02)
作者:Lei Zhang, Peng Luo, Xinggang Mao
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI:10.1016/j.bbamcr.2023.119509
影响因子 :5.100
引用产品:164210-50 CL-0012 CL-0237 CL-0238 CL-0458 CL-0583 PB180120 PM150210 PM150410
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A novel necroptosis-related gene signature for predict prognosis of glioma based on single-cell and bulk RNA sequencing.(2022/08/30)
作者:Kai Guo, Xinxin Duan, Jiahui Zhao
期刊:Frontiers in Molecular Biosciences
影响因子 :5.000
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Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway(2022/02/12)
作者:Jubo Wang, Yu Quan, Jian Lv
期刊:Environmental Toxicology
影响因子 :4.109
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GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma(2022/08/23)
作者:Zhaoshou Yang, Qin Yang, Xiaoxiao Sun
期刊:Journal of Immunology Research
影响因子 :4.100
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MiR-760 exerts a critical regulatory role in glioma proliferation, migration, and invasion by modulating MMP2 expression.(2024/04/08)
作者:Zhengting Qian, Heng Xin, Zhen Jia
期刊:Journal of Cancer
影响因子 :3.900
引用产品:CL-0458
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Comprehensive development and validation of gene signature for predicting survival in patients with glioblastoma.(2022/08/10)
作者:Yi Jin, Zhanwang Wang, Kaimin Xiang
期刊:Frontiers in Genetics
影响因子 :3.700
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