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产品概述
| 名称 | HEC-1-A (人子宫内膜腺癌细胞) (STR鉴定正确) |
| 别称 | Hec-1-A; HEC-1A; HEC1-A; HEC1A; Hec1A |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | HEC-1-A细胞及其亚株HEC-1-B细胞是H·Kuramoto及其同事于1968年从一位ⅠA期子宫内膜癌患者身上分离得到的。PAF可以诱导，HEC-1-A细胞c-fos的表达。 |
| 年龄（性别） | 女性；71岁 |
| 组织来源 | 腺癌；子宫；子宫内膜炎 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 子宫内膜腺癌 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~27-36 hours |
| 致瘤性 | Yes, in nude mice (The cells form moderately well differentiated adenocarcinomas consistent with endometrial carcinoma (grade II)).Yes, in the cheek pouch of cortisone treated hamsters (The cells form typical papillary adenomas). |
| 受体表达情况 | platelet activating factor (PAF) |
| 抗原表达情况 | Blood Type B; Rh+ |
| 基因表达情况 | c-fos+ |
| 保藏机构 | ATCC; HTB-112 BCRC; 60552 JCRB; JCRB1117 JCRB; NIHS0388 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,12 D2S1338 18,19 D3S1358 15 D5S818 11,15 D7S820 9,11 D8S1179 13,14 D13S317 11 D16S539 12 D18S51 16,21 D19S433 13 D21S11 30,31 FGA 21,22 PentaD 9,12,13 PentaE 11 TH01 6,7 TPOX 8,11 vWA 18,19,20 D6S1043 12,18 D12S391 19 D2S441 11,13 -
STR鉴定图
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参考文献
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Construction of the novel immune risk scoring system related to CD8+ T cells in uterine corpus endometrial carcinoma(2023/06/22)
作者：Ganghua Zhang, Zhijing Yin, Jianing Fang
期刊：Cancer Cell International
DOI：10.1186/s12935-023-02966-y
影响因子 ：5.800
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Comprehensive analysis and experimental validation reveal elevated CLCN4 is a promising biomarker in endometrial cancer(2023/09/05)
作者：Chenyang Wang, Jing Li, Weina Liu
期刊：Aging-US
影响因子 ：5.200
引用产品：CL-0099
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Mechanism of action of icaritin on uterine corpus endometrial carcinoma based on network pharmacology and experimental evaluation(2023/07/19)
作者：Yanbin Jin , Xiaochen Liang, Junhong Cai
期刊：Frontiers in Oncology
影响因子 ：4.700
引用产品：CL-0099
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Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma(2023/03/11)
作者：Wang Min, Yue Song, Yang Zhu
期刊：Scientific Reports
DOI：10.1038/s41598-023-31325-0
影响因子 ：4.600
引用产品：CL-0099
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SIM2: Its Prognostic Significance and Oncogenic Role in Endometrial Carcinoma(2024/01/26)
作者：Yunfang Wei, Xianlei Zhao, Hong Tang
期刊：OncoTargets and Therapy
影响因子 ：4.000
引用产品：CL-0099
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Ferroptosis-related lncRNA model based on CFAP58-DT for predicting prognosis and immunocytes infiltration in endometrial cancer(2023/02/10)
作者：Aijun Qin, Qiaoxia Qian, Xiaopei Cui
期刊：Annals of Translational Medicine
影响因子 ：3.616
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CMBs carrying PTX and CRISPR/Cas9 targeting C‑erbB‑2 plasmids interfere with endometrial cancer cells(2021/9/30)
作者：Siyuan Peng, Junhong Cai, Shan Bao
期刊：Molecular Medicine Reports
影响因子 ：3.400
引用产品：CL-0099
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ZAP70 interaction with 13 mRNAs as a potential immunotherapeutic target for endometrial cancer(2023/04/06)
作者：Yuming Zhang, Haiou Lu, Yuexin Yu
期刊：Oncology Letters
影响因子 ：2.900
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Friend leukemia integration 1 overexpression decreases endometrial receptivity and induces embryo implantation failure by promoting PART1 transcription in the endometrial epithelial cells(2023/09/26)
作者：Yile Zhang, Beining Yin, Sichen Li
期刊：PeerJ
影响因子 ：2.700
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Effects of RFRP‑3 on an ovariectomized estrogen‑primed rat model and HEC‑1A human endometrial carcinoma cells(2022/12/23)
作者：Xueying Zhao, Lina Si, Lin Niu
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.700
引用产品：CL-0099
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IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway(2023/03/03)
作者：Juan Gao, Shiqi Suo, Jingxia Li
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.700
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Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer(2024/04/24)
作者：Yuni Jin, Xiaoning Lu, Yuan Liu
期刊：CYTOTECHNOLOGY
DOI：10.1007/s10616-024-00629-y
影响因子 ：2.200
引用产品：CL-0099
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LINC01857 Exacerbates the Malignant Behaviors of Endometrial Carcinoma Cells by Sponging miR-19b-3p and Recruiting ELAVL1 to Upregulate MYCN(2023/03/28)
作者：Rong Cao, Jiao Zhao, Jingru Zhang
期刊：GYNECOLOGIC AND OBSTETRIC INVESTIGATION
影响因子 ：2.100
引用产品：CL-0099
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Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: A clue to enhance endometrial receptivity in recurrent implantation failure(2022/12/22)
作者：Haixia Li, Ning Su, Yaqiao Zhu
期刊：EUROPEAN JOURNAL OF HISTOCHEMISTRY
影响因子 ：1.966
引用产品：CL-0099
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