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产品概述
| 名称 | MH-S (小鼠肺泡巨噬细胞) (种属鉴定正确) |
| 种属 | 小鼠 |
| 生长特性 | 半贴半悬 |
| 细胞形态 | 巨噬细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The MH-S cell line was derived by SV40 transformation of an adherent cell enriched population of mouse alveolar macrophages. |
| 年龄（性别） | 雄性；7周龄 |
| 组织来源 | 肺巨噬细胞 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-2 |
| 抗原表达情况 | CD11b (Mac-1); Class II antigens (I-A); T antigen |
| 基因表达情况 | interleukin 1 (IL-1) |
| 保藏机构 | ATCC; CRL-2019 BCRC; 60419 ECACC; 95090612 |
STR鉴定
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STR位点信息
18-3 16 6-7 15 5-5 17 X-1 26,27 1-2 19 7-1 26.2 8-1 16 1-1 16 19-2 13 15-3 22.3 12-1 17 6-4 18 4-2 20.3 3-2 14 2-1 16 13-1 17.1,18.1
11-2 16 17-2 15 -
STR鉴定图
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参考文献
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Nebulized inhalation of nintedanib-loaded biomimetic nano-liposomes attenuated bleomycin-induced interstitial lung fibrosis in mice(2024/05/08)
作者：Le Rao, Pingjun Zhu, Mengyu Guo
期刊：Nano Today
DOI：10.1016/j.nantod.2024.102298
影响因子 ：17.400
引用产品：CL-0597
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Single-dose of hybrid eukaryotic-prokaryotic nanovesicles to drive a rapid and controllable immune response against Klebsiella pneumoniae induced nosocomial pneumonia(2023/12/28)
作者：Lai Jiang, Linyu Ding, Qiuyue Long
期刊：Nano Today
DOI：10.1016/j.nantod.2023.102135
影响因子 ：17.400
引用产品：CL-0597
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Ythdf2 promotes pulmonary hypertension by suppressing Hmox1-dependent anti-inflammatory and antioxidant function in alveolar macrophages(2023/02/15)
作者：Li Hu, Yanfang Yu, Yueyao Shen
期刊：Redox Biology
DOI：10.1016/j.redox.2023.102638
影响因子 ：11.400
引用产品：CL-0597
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Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NF-κB Signaling Pathway(2022/11/21)
作者：Caixia Li, Yuhong Li, Han Zhang, Yuzhen Zhuo, Lanqiu Zhang, Lei Yang, Qiaoying Gao, Zhengwei Tu, Rui Shao, Yu Wang, Junhua Zhang, Lihua Cui, Shukun Zhang
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154551
影响因子 ：7.900
引用产品：CL-0597
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Effective-components combination improves airway remodeling in COPD rats by suppressing M2 macrophage polarization via the inhibition of mTORC2 activity(2021/09/13)
作者：Lan Liu, Yanqin Qin, Zehui Cai
期刊：Phytomedicine
DOI：10.1016/j.phymed.2021.153759
影响因子 ：7.900
引用产品：CL-0597
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Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome(2023/12/18)
作者：Xiaohan Jing, Guanyu Zhao, Guibo Wang
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.116028
影响因子 ：7.500
引用产品：CL-0597
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Polyhexamethylene guanidine accelerates the macrophage foamy formation mediated pulmonary fibrosis(2024/02/13)
作者：He Sun, Zhijiao Yan, Jiaxing Sun
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116084
影响因子 ：6.800
引用产品：CL-0597
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5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway(2023/07/17)
作者：Yang Ma, Zhixue Wang, Xiaoyang Wu
期刊：INFLAMMATION RESEARCH
DOI：10.1007/s00011-023-01769-1
影响因子 ：6.700
引用产品：CL-0597
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Multi-omics and multi-stages integration identified a novel variant associated with silicosis risk(2024/05/29)
作者：Chunmeng Jin, Xiaobo Tao, Wendi Zhang
期刊：ARCHIVES OF TOXICOLOGY
DOI：10.1007/s00204-024-03795-2
影响因子 ：6.100
引用产品：CL-0597
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4-octyl itaconate ameliorates alveolar macrophage pyroptosis against ARDS via rescuing mitochondrial dysfunction and suppressing the cGAS/STING pathway(2023/03/31)
作者：Yutong Wu, Wenting Xu, Li Zheng
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110104
影响因子 ：5.600
引用产品：CL-0597
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MiR-223-3p attenuates radiation-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages(2023/07/16)
作者：Mingwei Zhang, Hailin Lan, Shaoli Peng
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110616
影响因子 ：5.600
引用产品：CL-0597
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A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages(2023/09/21)
作者：Xiaofei Shen, Hongqing Chen, Hai Zhang
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110965
影响因子 ：5.600
引用产品：CL-0597
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Cordyceps militaris Solid Medium Extract Alleviates Lipoteichoic Acid-Induced MH-S Inflammation by Inhibiting TLR2/NF-κB/NLRP3 Pathways(2023/10/24)
作者：Xiaoya Wang, Zhiping Peng, Lei Wang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0597
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Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis(2021/08/24)
作者：Yongqi Wang, Xiaoqing Wang, Hong Zhang
期刊：Frontiers in Cellular and Infection Microbiology
影响因子 ：5.500
引用产品：CL-0597
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Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection(2021/03/22)
作者：Huanhuan Ning, Wei Zhang, Jian Kang
期刊：Frontiers in Cellular and Infection Microbiology
影响因子 ：5.500
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A Flavonoid Glycoside Compound from Siraitia grosvenorii with Anti-Inflammatory and Hepatoprotective Effects In Vitro(2024/04/07)
作者：Juanjiang Wu, Huaxue Huang, Limin Gong
期刊：Biomolecules
影响因子 ：5.500
引用产品：CL-0597
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Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis(2023/10/28)
作者：Qian Wu, Mingyuan Zhou, Yuchi Chen
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0597
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Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD(2023/12/02)
作者：Jing Wang, Weijing He, Huiyu Yue
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0597
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MicroRNA-205-5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2-mediated Beclin1 ubiquitination(2021/08/27)
作者：Qingzeng Qian, Qinghua Ma, Bin Wang
期刊：Journal Of Cellular And Molecular Medicine
影响因子 ：5.300
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ANGPTL2 knockdown induces autophagy to relieve alveolar macrophage pyroptosis by reducing LILRB2-mediated inhibition of TREM2(2024/05/17)
作者：Fan Yang, Muhu Chen, Ying Liu
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.300
引用产品：CL-0597
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IRF4 Participates in Pulmonary Fibrosis Induced by Silica Particles through Regulating Macrophage Polarization and Fibroblast Activation(2023/11/08)
作者：Biyang Jiao, Qianyi Zhang, Chunmeng Jin
期刊：INFLAMMATION
DOI：10.1007/s10753-023-01890-7
影响因子 ：5.100
引用产品：CL-0597
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Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice(2024/05/07)
作者：Jingyue Chang, Xiaomeng Gao, Fan Yang
期刊：INFLAMMATION
DOI：10.1007/s10753-024-02030-5
影响因子 ：5.100
引用产品：CL-0597
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Upregulated expression of long non-coding RNA MEG3 serves as a prognostic biomarker in severe pneumonia children and its regulatory mechanism(2021/9/24)
作者：Jie Guo, Ning Zhang, Guozhi Liu
期刊：Bioengineered
DOI：10.1080/21655979.2021.1979351
影响因子 ：4.900
引用产品：CL-0597
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The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice(2024/05/22)
作者：Shirong Zhu, Xiaoling Wang, Gaoqiang Liu
期刊：Toxics
影响因子 ：4.600
引用产品：CL-0597
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Discovery of the Active Compounds of the Ethyl Acetate Extract Site of Ardisia japonica (Thunb.) Blume for the Treatment of Acute Lung Injury(2024/02/07)
作者：Shuding Sun, Xuefang Liu, Di Zhao
期刊：MOLECULES
影响因子 ：4.600
引用产品：CL-0597
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Identification of circRNA expression profiles and the potential role of hsa_circ_0006916 in silicosis and pulmonary fibrosis(2022/11/17)
作者：Qiuyun Wu, Biyang Jiao, Qianyi Zhang, Chunmeng Jin, Hongmin Yu, Feng Wang
期刊：TOXICOLOGY
影响因子 ：4.500
引用产品：CL-0597
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Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS-induced inflammation in vitro and in vivo(2022/09/23)
作者：Fei Peng, Xin Ren, Bin Du
期刊：Food Science & Nutrition
影响因子 ：3.900
引用产品：CL-0597
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Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages(2024/05/16)
作者：Liuling Luo, Huan Wang, Jinrui Xiong
期刊：PLoS One
DOI：10.1371/journal.pone.0303556
影响因子 ：3.700
引用产品：CL-0597
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3-O-trans-caffeoyloleanolic acid improves acute lung injury via anti-inflammation and antioxidative stress-involved PI3K/AKT pathway(2021/05/19)
作者：Jianhua Huang, Xueping Nong, Yanling Chen
期刊：Chemical Biology & Drug Design
影响因子 ：2.873
引用产品：CL-0597
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LncRNA NEAT1 Knockdown Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulation of miR-182-5p/WISP1 Axis(2021/05/27)
作者：Sensen Lv, Xiaolu Qu, Yan Qu
期刊：Biochemical Genetics
DOI：10.1007/s10528-021-10081-8
影响因子 ：2.400
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