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产品概述
| 名称 | RPMI 8226 (人多发性骨髓瘤外周血B淋巴细胞) (STR鉴定正确) |
| 别称 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no 8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; Simpson |
| 种属 | 人 |
| 生长特性 | 悬浮细胞 |
| 细胞形态 | 淋巴母细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 5-8×10^5 cells/mL |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 该细胞为悬浮细胞，请注意离心收集细胞悬液；请勿直接倒掉细胞培养液。 |
| 背景描述 | 没有证据表明，RPMI 8226细胞能产生重链(细胞质型或分泌型)。 |
| 年龄（性别） | 男性；61岁 |
| 组织来源 | 外周血，B淋巴细胞 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 骨髓瘤细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~60 hours |
| 保藏机构 | ATCC; CCL-155 ATCC; CRM-CCL-155 DSMZ; ACC-402 ECACC; 87012702 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 12 D2S1338 20 D3S1358 16,17 D5S818 11,13 D7S820 9,10 D8S1179 13 D13S317 11 D16S539 9 D18S51 15,19 D19S433 13.2,14 D21S11 28,29 FGA 19 PentaD 2.2,11 PentaE 16 TH01 8 TPOX 8,11 vWA 16,18 D6S1043 14,18 D12S391 16,19 D2S441 12,14 -
STR鉴定图
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参考文献
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Targeting Senescent Alveolar Epithelial Cells Using Engineered Mesenchymal Stem Cell-Derived Extracellular Vesicles To Treat Pulmonary Fibrosis(2024/02/21)
作者：Yaoying Long, Bianlei Yang, Qian Lei
期刊：ACS Nano
影响因子 ：17.100
引用产品：CL-0564
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Stimulus-Responsive Microfluidic Interface Enables Efficient Enrichment and Cytogenetic Profiling of Circulating Myeloma Cells(2021/03/23)
作者：Yilong Liu, Rui Su, Juan Song
期刊：ACS Applied Materials & Interfaces
影响因子 ：9.500
引用产品：CL-0564
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Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf(2020/09/30)
作者：Yujia Xu, Tong Sun, Kun Zeng
期刊：Cell Death & Disease
DOI：10.1038/s41419-020-03017-4
影响因子 ：9.000
引用产品：CL-0564
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NCX1/Ca2+ promotes autophagy and decreases bortezomib activity in multiple myeloma through non-canonical NFκB signaling pathway(2024/05/06)
作者：Tingting Li, Pingping Xiao, Dongbiao Qiu
期刊：Cell Communication and Signaling
DOI：10.1186/s12964-024-01628-4
影响因子 ：8.400
引用产品：CL-0564
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Ethanol Extract of Eclipta prostrata induces Multiple Myeloma Ferroptosis via Keap1/Nrf2/HO-1 Axis(2024/02/01)
作者：Wenxia Li, Xuejiao Yin, Hangjie Fu
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155401
影响因子 ：7.900
引用产品：CL-0564
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Lnc NEAT1/miR-29b-3p/Sp1 form a positive feedback loop and modulate bortezomib resistance in human multiple myeloma cells(2020/11/28)
作者：Feifei Che, Xuemei Ye, Yu Wang
期刊：European Journal Of Pharmacology
DOI：10.1016/j.ejphar.2020.173752
影响因子 ：5.000
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NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis(2022/09/17)
作者：Tao Ma, Yan Chen, Zhigang Yi
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2022.110474
影响因子 ：4.800
引用产品：CL-0564
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LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma(2023/07/18)
作者：Zhigang Yi, Tao Ma, Jia Liu
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110814
影响因子 ：4.800
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Quercetin inhibits the proliferation of multiple myeloma cells by upregulating PTPRR expression(2021/09/24)
作者：Houcai Wang, Dandan Yu, Hui Zhang
期刊：Acta Biochimica Et Biophysica Sinica
影响因子 ：3.511
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LAMP5 may promote MM progression by activating p38(2023/03/22)
作者：Chen Yan, Ma Tao
期刊：PATHOLOGY & ONCOLOGY RESEARCH
影响因子 ：2.800
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Design, synthesis, and in vitro biological evaluation of novel HDAC inhibitors bearing C-1 phenyl substituted tetrahydroisoquinoline Cap moiety as anti-tumor therapeutic agents(2024/03/27)
作者：Jie Wang, Chi Zhou, Bo Li
期刊：MEDICINAL CHEMISTRY RESEARCH
DOI：10.1007/s00044-024-03206-2
影响因子 ：2.600
引用产品：CL-0564
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Hsa_Circ_0134426 Attenuates the Malignant Biological Behaviors of Multiple Myeloma by Suppressing miR-146b-3p to Upregulate NDNF(2022/12/02)
作者：Menglan Li, Jingyuan Li, Yanyan Song
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-022-00618-6
影响因子 ：2.600
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Expression of STOML2 promotes proliferation and glycolysis of multiple myeloma cells via upregulating PAI-1(2021/11/13)
作者：Hongxia Zhang, Guangsheng Wu, Junjian Feng
期刊：Journal of Orthopaedic Surgery and Research
DOI：10.1186/s13018-021-02819-2
影响因子 ：2.600
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