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产品概述
名称 | MKN-45 (人胃癌细胞)(STR鉴定正确) |
种属 | 人 |
生长特性 | 半贴半悬 |
细胞形态 | 圆形 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | MKN-45 细胞是由 Hojo H建立,源于日本一位62岁低分化胃腺癌女性患者的肝转移灶。 |
年龄(性别) | 女性;62岁 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胃癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~30-60 hours |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 18 D3S1358 15,16 D5S818 10,11 D7S820 10,11 D8S1179 13,17 D13S317 8,11 D16S539 10 D18S51 16 D19S433 14,16.2 D21S11 31 FGA 19,24 PentaD 10 PentaE 10 TH01 7 TPOX 8 vWA 19 D6S1043 14 D12S391 26 D2S441 11 -
STR鉴定图
参考文献
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Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors(2023/10/24)
作者:Xiuxiu Zhu, Jun Chen, Wuling Li
期刊:CANCER RESEARCH
DOI:10.1158/0008-5472.CAN-23-1038
影响因子 :11.200
引用产品:CL-0292
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Neutrophil extracellular traps promote angiogenesis in gastric cancer(2023/07/21)
作者:Shifeng Yang, Boshi Sun, Jiacheng Li
期刊:Cell Communication and Signaling
DOI:10.1186/s12964-023-01196-z
影响因子 :8.400
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A novel human single-domain antibody-drug conjugate targeting CEACAM5 exhibits potent in vitro and in vivo antitumor activity(2023/11/29)
作者:Xiaoyi Zhu, Quanxiao Li, Yu Kong
期刊:ACTA PHARMACOLOGICA SINICA
DOI:10.1038/s41401-023-01200-9
影响因子 :8.200
引用产品:CL-0292
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CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1(2022/11/12)
作者:Li, Dongbao, Wang, Yuhong, Dong, Chao, Chen, Tao, Dong, Anqi, Ren, Jiayu, Li, Weikang, Shu, Gege, Yang, Jiaoyang, Shen, Wenhao, Qin, Lei, Hu, Lin, Zhou, Jin
期刊:ONCOGENE
DOI:10.1038/s41388-022-02537-x
影响因子 :8.000
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Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis(2023/01/05)
作者:Chenggang Zhang, Guanxin Wei, Xiuxian Zhu
期刊:International Journal of Nanomedicine
影响因子 :8.000
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Compound Kushen Injection inhibits epithelial-mesenchymal transition of gastric carcinoma by regulating VCAM1 induced by the TNF signaling pathway(2023/07/17)
作者:Zhihong Huang, Chao Wu, Wei Zhou
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2023.154984
影响因子 :7.900
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The regulatory role of cancer stem cell marker gene CXCR4 in the growth and metastasis of gastric cancer(2023/09/07)
作者:Hongying Zhao, Rongke Jiang, Chunmei Zhang
期刊:npj Precision Oncology
DOI:10.1038/s41698-023-00436-2
影响因子 :7.900
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CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation(2024/03/08)
作者:Yongxin Zhang, Xiaofeng Wang, Wenwei Liu
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04625-2
影响因子 :7.400
引用产品:CL-0292
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Quercetin induces ferroptosis in gastric cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1 and NRF2/GPX4 Axes(2024/01/06)
作者:Lixian Ding, Shuwei Dang, Mingjun Sun
期刊:FREE RADICAL BIOLOGY AND MEDICINE
DOI:10.1016/j.freeradbiomed.2024.01.002
影响因子 :7.400
引用产品:CL-0292
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Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer(2023/01/05)
作者:Hao Yang, Xinyi Gou, Caizhen Feng
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-022-03845-2
影响因子 :7.400
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Identification of lactylation related model to predict prognostic, tumor infiltrating immunocytes and response of immunotherapy in gastric cancer(2023/03/03)
作者:Hao Yang, Xiaoming Zou, Shifeng Yang
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1149989
影响因子 :7.300
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Microfluidic device featuring micro-constrained channels for multi-parametric assessment of cellular biomechanics and high-precision mechanical phenotyping of gastric cells(2024/03/12)
作者:Yang Heng, Xinyu Zheng, Youyuan Xu
期刊:ANALYTICA CHIMICA ACTA
影响因子 :6.200
引用产品:CL-0292
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RP11-789C1.1 inhibits gastric cancer cell proliferation and accelerates apoptosis via the ATR/CHK1 signaling pathway(2023/10/25)
作者:Wenwei Liu, Wei Feng, Yongxin Zhang
期刊:CHINESE MEDICAL JOURNAL
DOI:10.1097/CM9.0000000000002869
影响因子 :6.100
引用产品:CL-0292
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Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer(2023/12/01)
作者:Hao Yang, Shifeng Yang, Jixing He
期刊:Cancer Cell International
DOI:10.1186/s12935-023-03162-8
影响因子 :5.800
引用产品:CL-0292
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Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma(2022/11/23)
作者:Yun Li, Jian-Bo Xiong, Zhi-Gang Jie, Hui Xiong
期刊:Frontiers in Oncology
影响因子 :5.738
引用产品:CL-0292
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CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3(2024/02/29)
作者:Gengchen Xie, Bo Lei, Zhijie Yin
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.600
引用产品:CL-0292
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Cytotoxic and Antibacterial Meroterpenoids Isolated from the Marine-Derived Fungus Talaromyces sp. M27416(2024/04/20)
作者:Lingzhi Tang, Jinmei Xia, Zhongwei Chen
期刊:Marine Drugs
影响因子 :5.400
引用产品:CL-0292
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Insights into the inhibition of stomach cancer MKN45 cell growth by Poria cocos ethanol-soluble extract based on MAPK/PI3K signaling pathways and components cell fishing(2023/11/17)
作者:Zhenni Xie, Hongliang Zeng, Dan He
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.400
引用产品:CL-0292
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LINC01354 enhances the metastatic ability of gastric cancer cells by adjusting miR-153-5p/CADM2 expression(2023/06/15)
作者:Fa Fang, Yin Gu, Jie Gao
期刊:American Journal of Cancer Research
DOI:PMID:37424819
影响因子 :5.300
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ESM1 Interacts with c-Met to Promote Gastric Cancer Peritoneal Metastasis by Inducing Angiogenesis(2023/12/30)
作者:Jiaoyang Yang, Gege Shu, Tao Chen
期刊:Cancers
影响因子 :5.200
引用产品:CL-0292
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Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase(2023/09/28)
作者:Minghui Liu, Shibo Sun, Yao Meng
期刊:MOLECULES
影响因子 :4.600
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Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis(2021/04/20)
作者:Haifeng Gao, Jiajia Xu, Fen Qiao
期刊:OncoTargets and Therapy
影响因子 :4.345
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Bile acids inhibit ferroptosis sensitivity through activating farnesoid X receptor in gastric cancer cells(2024/02/07)
作者:Chuxuan Liu, Ying Gao, Xiufang Xu
期刊:WORLD JOURNAL OF GASTROENTEROLOGY
影响因子 :4.300
引用产品:CL-0292
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Macrophage-derived exosomes regulate gastric cancer cell oxaliplatin resistance by wrapping circ 0008253(2022/11/23)
作者:Dandan Yu, Zhiwei Chang, Xiaolei Liu, Pengfei Chen, Huixian Zhang, Yanru Qin
期刊:CELL CYCLE
DOI:10.1080/15384101.2022.2146839
影响因子 :4.300
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18β-glycyrrhetinic acid inhibits proliferation of gastric cancer cells through regulating the miR-345-5p/TGM2 signaling pathway(2023/06/21)
作者:Xia Li, Xiaoling Ma, Yi Nan
期刊:WORLD JOURNAL OF GASTROENTEROLOGY
影响因子 :4.300
引用产品:CL-0292
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Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis(2023/04/07)
作者:Haifeng Gao, Jiajia Xu, Fen Qiao
期刊:OncoTargets and Therapy
影响因子 :4.000
引用产品:CL-0292
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CIZ1 aggravates gastric cancer progression via mediating FBXL19-AS1 and miR-339-3p(2023/10/14)
作者:Houmin Wan, Lianzhen Wang, Bin Huo
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e21061
影响因子 :4.000
引用产品:CL-0292
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LncRNA SNHG6 knockdown inhibits cisplatin resistance and progression of gastric cancer through miR-1297/BCL-2 axis(2021/12/22)
作者:Jiazhan Mei, Guiju Liu, Ruijun Li
期刊:Bioscience Reports
影响因子 :4.000
引用产品:CL-0292
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Suppression of gastric cancer cell proliferation by miR-494-3p inhibitor-loaded engineered exosomes(2024/05/06)
作者:Limin Zhang, Yingwei Xue, Hongfeng Zhang
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e30803
影响因子 :4.000
引用产品:CL-0292
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Identification of A Novel Gene Signature Combining Ferroptosis- and Immunity-Related Genes for Prognostic Prediction, Immunotherapy and Potential Therapeutic Targets in Gastric Cancer(2023/10/16)
作者:Liwei Wang, Zhuozhuo Li, Zi Li
期刊:Journal of Cancer
影响因子 :3.900
引用产品:CL-0292
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TYMSOS drives the proliferation, migration, and invasion of gastric cancer cells by regulating ZNF703 via sponging miR-4739(2021/4/12)
作者:Yulan Gu, Chuandan Wan, Guoqiang Zhou
期刊:Cell Biology International
影响因子 :3.900
引用产品:CL-0292
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Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway(2022/03/02)
作者:Dong Tan, Yafei Zhang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2022.115968
影响因子 :3.800
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YTHDF2 promotes gastric cancer progression and enhances chemoradiotherapy resistance(2024/04/14)
作者:Jian Yang, Yawen Chen, Yang He
期刊:DRUG DEVELOPMENT RESEARCH
影响因子 :3.800
引用产品:CL-0292
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Closed-loop of Catalyzed Lactate Oxidization Synergistically Sensitizes Apoptosis and Ferroptosis for Cancer Therapy(2024/02/01)
作者:Yajun Ma, Jianquan Chen, Yan Yang
期刊:ChemNanoMat
影响因子 :3.800
引用产品:CL-0292
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Upregulation of E-cadherin by the combination of methionine restriction and HDAC2 intervention for inhibiting gastric carcinoma metastasis: Synergetic MR and HDAC2 intervention in GC metastasis(2023/12/21)
作者:Yifan Li, Chenxi Liu, Lin Xin
期刊:ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影响因子 :3.700
引用产品:CL-0292
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PKNOX1 acts as a transcription factor of DHH and promotes the progression of stomach adenocarcinoma by regulating the Hedgehog signalling pathway(2023/10/21)
作者:Bing Liu, Siwei Zhao, Liqing Liu
期刊:INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
影响因子 :3.500
引用产品:CL-0292
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Long non‑coding RNA lnc‑GNAT1‑1 inhibits gastric cancer cell proliferation and invasion through the Wnt/β‑catenin pathway in Helicobacter pylori infection(2018/8/20)
作者:Liping Liu, Tiankui Shuai, Bin Li
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0292
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Long Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin Axis(2023/01/30)
作者:Xiaofeng Cui, Huaiyu Zhang, Tong Chen
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:CL-0292
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Long Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin Axis(2020/12/15)
作者:Xiaofeng Cui, Huaiyu Zhang, Tong Chen
期刊:Cancer Management and Research
影响因子 :3.300
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CREB1 Suppresses Transcription of microRNA-186 to Promote Growth, Invasion and Epithelial–Mesenchymal Transition of Gastric Cancer Cells Through the KRT8/HIF-1α Axis(2020/9/25)
作者:Xue Huang, Fujian Liu, Zhiyong Jiang
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:CL-0292
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The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells(2023/07/24)
作者:Guangyi Liu, Huan Wang, Rui Ran
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.07.038
影响因子 :3.100
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Homeobox Protein BarH-like 1 Promotes Gastric Cancer Progression by Activating Coiled-Coil Domain-Containing Protein 178(2024/02/15)
作者:Yue Gu, Gang Chen, Xinwei Ning
期刊:DIGESTIVE DISEASES AND SCIENCES
DOI:10.1007/s10620-024-08312-0
影响因子 :3.100
引用产品:CL-0292
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Immune-related long noncoding RNA zinc finger protein 710-AS1-201 promotes the metastasis and invasion of gastric cancer cells(2024/02/15)
作者:Wei Ding, Weiwei Chen, Yiqin Wang
期刊:World Journal of Gastrointestinal Oncology
影响因子 :3.000
引用产品:CL-0292
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Flavonoid-Rich Extract of Oldenlandia diffusa (Willd.) Roxb. Inhibits Gastric Cancer by Activation of Caspase-Dependent Mitochondrial Apoptosis(2022/08/31)
作者:Jiayin Ling, Qiulan Wang, Haonan Liang
期刊:Chinese Journal of Integrative Medicine
影响因子 :2.900
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A prognostic marker LTBP1 is associated with epithelial mesenchymal transition and can promote the progression of gastric cancer(2024/02/15)
作者:Xinju Jiang, Shengjie Yin, Xin Yin
期刊:FUNCTIONAL & INTEGRATIVE GENOMICS
DOI:10.1007/s10142-024-01311-4
影响因子 :2.900
引用产品:CL-0292
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KBTBD2 promotes proliferation and migration of gastric cancer via activating EGFR signaling pathway(2024/01/04)
作者:Jishuang Ding, Wei Gao, Haiying Yang
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.800
引用产品:CL-0292
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Transcription factor E2F3 activates CDC25B to regulate DNA damage and promote mitoxantrone resistance in stomach adenocarcinoma(2024/01/09)
作者:Xiaoming Pan, Chaobo Xu, Guoxiong Cheng
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08933-0
影响因子 :2.800
引用产品:CL-0292
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Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells(2022/12/08)
作者:Jiang Liu, LiJun Ren, HaoWen Wang
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10309-1
影响因子 :2.400
引用产品:CL-0292
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Oncogenic transmembrane protein 158 drives the PI3K/Akt signaling pathway to accelerate gastric cancer cell growth(2023/11/13)
作者:Xiaoting Cui, Jie Lu, Cuijuan Zhao
期刊:BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
DOI:10.1590/1414-431X2023e12943
影响因子 :2.300
引用产品:CL-0292
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A new anthraquinone derivative from the marine fish-derived fungus Alternaria sp. X112(2023/09/13)
作者:Xiaoyuan Xu, Gang Li, Rao Fu
期刊:NATURAL PRODUCT RESEARCH
DOI:10.1080/14786419.2023.2258540
影响因子 :2.200
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Curcumin suppresses the progression of gastric cancer by regulating circ_0056618/miR-194-5p axis(2021/1/1)
作者:Shan Li, Lihai Zhang, Shuhua Li
期刊:Open Life Sciences
影响因子 :2.200
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RNA-binding protein ENO1 promotes the tumor progression of gastric cancer by binding to and regulating gastric cancer-related genes(2023/04/17)
作者:Na Wang, Hui Qiao, Jianpeng Hao
期刊:Journal of Gastrointestinal Oncology
影响因子 :2.100
引用产品:CL-0292
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Knockdown of kinesin family member 2C restricts cell proliferation and induces cell cycle arrest in gastric cancer(2022/11/30)
作者:Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou, Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000
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Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis(2022/10/03)
作者:Jinbi Xie, Yong Ning, Lihang Zhang
期刊:EUROPEAN JOURNAL OF HISTOCHEMISTRY
影响因子 :1.966
引用产品:CL-0292
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