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产品概述
| 名称 | HFL1 (人胚肺成纤维细胞) (STR鉴定正确) |
| 别称 | HFL-1; HFL 1; Human fetal lung fibroblast 1; HFL |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 该细胞为有限传代细胞系，传代次数过高会导致细胞生长特性发生变化，建议到货3代内完成实验。 |
| 年龄（性别） | 男性；胎儿 |
| 组织来源 | 肺 |
| 细胞类型 | 有限细胞系 |
| 生物安全等级 | BSL-1 |
| 保藏机构 | ATCC; CCL-153 BCRC; 60299 ECACC; 89071902 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 17,25 D3S1358 14,17 D5S818 12 D7S820 9,10 D8S1179 12,14 D13S317 11,12 D16S539 9,11 D18S51 18,19 D19S433 11,13 D21S11 27,30 FGA 21,22 PentaD 2.2,9 PentaE 12,20 TH01 7,9 TPOX 6,9 vWA 17 D6S1043 11,18 D12S391 20,21 D2S441 14,15 -
STR鉴定图
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参考文献
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Combating Atherosclerosis with Chirality/Phase Dual-Engineered Nanozyme Featuring Microenvironment-Programmed Senolytic and Senomorphic Actions(2024/05/09)
作者：Chengjin Ding, Jiao Min, Yongkang Tan
期刊：ADVANCED MATERIALS
影响因子 ：29.400
引用产品：CL-0106
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UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment(2024/02/08)
作者：Yin Li, Manling Jiang, Ling Aye
期刊：Nature Communications
DOI：10.1038/s41467-024-45340-w
影响因子 ：16.600
引用产品：CL-0106
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Templated freezing assembly precisely regulates molecular assembly for free-standing centimeter-scale microtextured nanofilms(2023/02/07)
作者：Junqiang Mao, Huimei Cao, Jie Liu
期刊：Science China-Chemistry
影响因子 ：9.600
引用产品：CL-0106
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Yangqing Chenfei formula attenuates silica-induced pulmonary fibrosis by suppressing activation of fibroblast via regulating PI3K/AKT, JAK/STAT, and Wnt signaling pathway(2022/12/22)
作者：Fan Yang, Runsu Hou, Xinguang Liu
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154622
影响因子 ：7.900
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Forsythoside A regulates pulmonary fibrosis by inhibiting endothelial-to-mesenchymal transition and lung fibroblast proliferation via the PTPRB signaling(2024/05/10)
作者：Qinqin Zhang, Beibei Zhang, Fan Yang
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155715
影响因子 ：7.900
引用产品：CL-0106
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Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro(2019/03/04)
作者：Deguang Kong, Dan Zhang, Qiuxia Cui
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2019.108706
影响因子 ：7.500
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Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction(2024/03/10)
作者：Wenhua Gan, Wenwen Song, Yujuan Gao
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05034-9
影响因子 ：7.400
引用产品：CL-0106
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Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes(2024/01/25)
作者：Maolin Li, Letian Dai, Zhuoyu Gao
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01773
影响因子 ：7.300
引用产品：CL-0106
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Inhibition of DNA methylation derepresses PPARγ and attenuates pulmonary fibrosis(2021/08/11)
作者：Ai Wei, Qi Gao, Fang Chen
期刊：British Journal Of Pharmacology
影响因子 ：7.300
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p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin(2022/02/03)
作者：Qian Zeng, Tingting Zhou, Feiyan Zhao
期刊：Antioxidants
影响因子 ：7.000
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Assessment of 2-allyl-4,5-dimethoxyphenol safety and attractiveness to mature males of Bactrocera dorsalis (Hendel)(2021/08/04)
作者：Shuzhen Deng, Xinyang Li, Ziming Wang
期刊：Ecotoxicology And Environmental Safety
DOI：10.1016/j.ecoenv.2021.112567
影响因子 ：6.800
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Dual inhibitors of ASK1 and PDK1 kinases: Design, synthesis, molecular docking and mechanism studies of N-benzyl pyridine-2-one containing derivatives as anti-fibrotic agents(2022/12/30)
作者：Jia Qin, Meng Cao, Xinlan Hu
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2022.115057
影响因子 ：6.700
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Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway(2024/01/14)
作者：Yin Zhang, Yongbo Lu, Weijie Zhu
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0106
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Total flavonoids of Oxytropis falcata Bunge have a positive effect on idiopathic pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway(2021/11/24)
作者：Xinze Li, Xuelin Wang, Yanjun Wang
期刊：Journal of Ethnopharmacology
影响因子 ：5.400
引用产品：CL-0106
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Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ(2023/09/07)
作者：Qian Zeng, Tingting Zhou, Wenjie Huang
期刊：Scientific Reports
DOI：10.1038/s41598-023-41933-5
影响因子 ：4.600
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IL-38 alleviates airway remodeling in chronic asthma via blocking the profibrotic effect of IL-36γ(2023/08/16)
作者：Min Zhang, Jianxia Zhou, Chuqin Huang
期刊：CLINICAL AND EXPERIMENTAL IMMUNOLOGY
影响因子 ：4.600
引用产品：CL-0106
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Dynamic phenotypic reprogramming and chemoresistance induced by lung fibroblasts in small cell lung cancer(2024/02/05)
作者：Yuanhua Lu, Hui Li, Peiyan Zhao
期刊：Scientific Reports
DOI：10.1038/s41598-024-52687-z
影响因子 ：4.600
引用产品：CL-0106
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A transcriptomics-based investigation of the mechanism of pulmonary fibrosis induced by nickel oxide nanoparticles(2024/01/02)
作者：Han Liu, Mengmeng Yang, Kun Li
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.500
引用产品：CL-0106
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Assessment of attractancy and safeness of (E)-coniferyl alcohol for management of female adults of Oriental fruit fly, Bactrocera dorsalis (Hendel)(2021/11/23)
作者：Huan Liu, Dandan Wang, Lin Wan
期刊：Pest Management Science
DOI：10.1002/ps.6713
影响因子 ：4.100
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Exploration of Clove Bud (Syzygium aromaticum) Essential Oil as a Novel Attractant against Bactrocera dorsalis (Hendel) and Its Safety Evaluation(2022/10/09)
作者：Zhenjie Hu, Jingwei Yang, Zihan Chen
期刊：Insects
影响因子 ：3.000
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Platycodin D ameliorates ammonia-induced pulmonary fibrosis by repressing TGF-β1-mediated extracellular matrix remodeling(2024/01/04)
作者：Wenqi Lian, Shihao Ge, Quanhai Pang
期刊：Chemical Biology & Drug Design
影响因子 ：3.000
引用产品：CL-0106
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Astragaloside IV restrains pulmonary fibrosis progression via the circ_0008898/miR-211-5p/HMGB1 axis(2024/03/21)
作者：Min Zhu, Limin Zhao, Xueying Zhang
期刊：Chemical Biology & Drug Design
影响因子 ：3.000
引用产品：CL-0106
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Metformin attenuates TGF-β1-induced pulmonary fibrosis through inhibition of transglutaminase 2 and subsequent TGF-β pathways(2020/06/03)
作者：Yubo Wang, Caiyu Lin, Rui Han
期刊：3 BIOTECH
DOI：10.1007/s13205-020-02278-2
影响因子 ：2.800
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JAK2 inhibitors improve RA combined with pulmonary fibrosis in rats by downregulating SMAD3 phosphorylation(2024/05/05)
作者：Yimei Wei, Dandan Wang, Juan Wu
期刊：International Journal of Rheumatic Diseases
影响因子 ：2.500
引用产品：CL-0106
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Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway(2023/08/28)
作者：Hongli Liu, Yan Yang, Jie Zhang
期刊：Advances in Rheumatology
DOI：10.1186/s42358-023-00325-z
影响因子 ：2.300
引用产品：CL-0106
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