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产品概述
Ham's F-12K培养基是Ham's F-12营养混合物的Kaighn's改进型,在Ham's F-12的基础上提高了氨基酸和丙酮酸的浓度,降低了葡萄糖的用量,并修改了盐的成分和含量(Konigsbergs)。Ham's F-12K培养基最初设计用于培养原代人肝细胞以及分化的大鼠和鸡的细胞。
本产品含有多类细胞培养所需的氨基酸、维生素、无机盐等多种成分,但不含蛋白质、脂类或任何生长因子,故此产品需搭配血清或无血清添加物使用。
成分说明
形态 | 液体 |
浓度 | 1× |
规格 | 500mL |
pH | 7.2-7.4 |
L-谷氨酰胺 | 2 mM |
NaHCO3 | 2500 mg/L |
D-葡萄糖 | 1260 mg/L |
HEPES缓冲剂 | 无 |
酚红指示剂 | 3 mg/L |
储存条件 | 2-8℃,避光 |
运输条件 | 常温 |
有效期 | 18个月 |
注意事项
1、本产品经0.1 μm过滤除菌,使用时应注意无菌操作,避免污染;
2、为保持本产品的最佳使用效果,请勿进行冻融处理;
3、本产品仅用于科研或进一步研究使用,不用于诊断和治疗。
参考文献
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Immunomodulatory effect and safety of TNF-α RNAi mediated by oral yeast microcapsules in rheumatoid arthritis therapy(2022/08/07)
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Melatonin ameliorates bleomycin-induced pulmonary fibrosis via activating NRF2 and inhibiting galectin-3 expression(2022/11/04)
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作者:Keheng Chen, Xin Zhang, Guangyu Sun
期刊:JOURNAL OF PROTEOME RESEARCH
DOI:10.1021/acs.jproteome.3c00655
影响因子 :4.400
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Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling(2022/10/31)
作者:Zhenming Gao, Jidong Sui, Rong Fan
期刊:Drug Design Development and Therapy
影响因子 :4.319
引用产品:PM150910
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Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer(2020/06/28)
作者:Dingsheng Liu, Hong Zhang, Mingming Cui
期刊:Cell Cycle
DOI:10.1080/15384101.2020.1783058
影响因子 :4.300
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Tanshinone IIA (TSIIA) represses the progression of non-small cell lung cancer by the circ_0020123/miR-1299/HMGB3 pathway(2022/12/31)
作者:Fei Sun, Xiaoli Yang, Wei Song
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-022-04646-3
影响因子 :4.300
引用产品:164210 164210-50 CL-0016 CL-0167 PB180120 PM150110 PM150910
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YAP1 inhibits RSL3-induced castration-resistant prostate cancer cell ferroptosis by driving glutamine uptake and metabolism to GSH(2023/09/29)
作者:Xian Fu, Hongshen Wu, Changjiu Li
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-023-04847-4
影响因子 :4.300
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Regulation of tumorigenesis and ferroptosis in non-small cell lung cancer by a novel BBOX1-AS1/miR-326/PROM2 axis(2023/08/28)
作者:Jinlu An, Jiang Shi, Chao Yang
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-023-04837-6
影响因子 :4.300
引用产品:CL-0016 CL-0165 CL-0213 CL-0402 PM150110 PM150210 PM150410 PM150910
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CircRNA OXCT1 promotes the malignant progression and glutamine metabolism of non-small cell lung cancer by absorbing miR-516b-5p and upregulating SLC1A5(2023/03/02)
作者:Hua Luo, Jianming Peng, Yuexi Yuan
期刊:CELL CYCLE
DOI:10.1080/15384101.2022.2071565
影响因子 :4.300
引用产品:PM150910
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Circ_0025039 acts an oncogenic role in the progression of non-small cell lung cancer through miR-636-dependent regulation of CORO1C(2022/01/16)
作者:Lei Wang, Cimei Zeng, Zhongren Chen
期刊:Molecular and Cellular Biochemistry
DOI:10.1007/s11010-021-04320-0
影响因子 :4.300
引用产品:164210 164210-50 CL-0016 CL-0165 PB180120 PM150110 PM150910
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SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo(2023/01/11)
作者:Yang Liu, Xiaoxi Fan, Changrui Jiang
期刊:Human Cell
DOI:10.1007/s13577-023-00855-0
影响因子 :4.300
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Network pharmacology‑based investigation of potential targets of triptonodiol acting on non-small-cell lung cancer(2023/11/28)
作者:Feng Jin, Xiaochen Ni, Shilong Yu
期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI:10.1186/s40001-023-01453-4
影响因子 :4.200
引用产品:PM150910
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MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2(2020/6/26)
作者:Haijun Wang, Zheng Wei, Hulun Li
期刊:Bioscience Reports
影响因子 :4.000
引用产品:PM150910
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RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway(2022/09/24)
作者:Jingsong Yu, Haipeng Qi, Zheng Wang
期刊:CELL BIOLOGY INTERNATIONAL
影响因子 :3.900
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Methyl-β-cyclodextrin suppresses the monocyte-endothelial adhesion triggered by lipopolysaccharide (LPS) or oxidized low-density lipoprotein (oxLDL)(2021/08/06)
作者:Guo Chen, Yun Zhou, Wendiao Zhang
期刊:Pharmaceutical Biology
DOI:10.1080/13880209.2021.1953540
影响因子 :3.889
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PUM2 regulates the formation of thoracic aortic dissection through EFEMP1(2023/04/14)
作者:Kangkang Zhi, Renqi Yin, Hongbo Guo
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2023.113602
影响因子 :3.700
-
PCSK9 inhibitor inclisiran for treating atherosclerosis via regulation of endothelial cell pyroptosis(2022/11/01)
作者:Ni Kong, Qin Xu, Wei Cui
期刊:Annals of Translational Medicine
影响因子 :3.616
引用产品:PM150910
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Circ-SATB2 (hsa_circ_0008928) and miR-150-5p are regulators of TRIM66 in the regulation of NSCLC cell growth and metastasis of NSCLC cells via the ceRNA pathway(2023/12/12)
作者:Liangji Chen, Yuting Zhou, Hongbing Cheng
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.600
引用产品:PM150910
-
CircDUS2L (circ_0039908) promotes lung adenocarcinoma progression by upregulating PGAM1 by acting as a miR-590-5p molecular sponge(2023/07/01)
作者:Qing Tian, Ying Guo, Jinfeng Liu
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.600
引用产品:CL-0005 CL-0016 CL-0668 PB180120 PM150110 PM150210 PM150910
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Hispidulin targets PTGS2 to improve cyclophosphamide-induced cystitis by suppressing NLRP3 inflammasome(2024/02/07)
作者:Songlin Liu, Shuhang Li, Yuping Dong
期刊:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI:10.1007/s00210-024-02987-y
影响因子 :3.600
引用产品:PM150910
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Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway(2024/01/12)
作者:Dong Yuan, Zhipeng Zheng, Cheng Shen
期刊:MOLECULAR IMMUNOLOGY
DOI:10.1016/j.molimm.2024.01.002
影响因子 :3.600
引用产品:PM150910
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P2X7 receptor promotes migration and invasion of non-small cell lung cancer A549 cells through the PI3K/Akt pathways(2023/03/01)
作者:Xue Bai, Qianqian Li, Xiaoxiang Peng
期刊:Purinergic Signalling
DOI:10.1007/s11302-023-09928-z
影响因子 :3.500
引用产品:PM150910
-
Targeting CAMK2N1/CAMK2 inhibits invasion, migration and angiogenesis of non-small cell lung cancer by promoting autophagy and apoptosis via AKT/mTOR signaling pathway(2024/03/14)
作者:Qiang Wang, Chao Zhang, Hai Jiang
期刊:GENE
DOI:10.1016/j.gene.2024.148375
影响因子 :3.500
引用产品:PM150910
-
Methylophiopogonanone B of Radix Ophiopogonis protects cells from H2O2‑induced apoptosis through the NADPH oxidase pathway in HUVECs(2019/8/29)
作者:Liling Wang, Yifeng Zhou, Yuchuan Qin
期刊:Molecular Medicine Reports
影响因子 :3.400
-
Rosuvastatin protects against oxidized low‑density lipoprotein‑induced endothelial cell injury of atherosclerosis in vitro(2018/11/19)
作者:Jianan Geng, Huali Xu, Xiaofeng Yu
期刊:Molecular Medicine Reports
影响因子 :3.400
-
MiR-214-3p overexpression-triggered chondroitin polymerizing factor (CHPF) inhibition modulates the ferroptosis and metabolism in colon cancer(2024/01/08)
作者:Zhiyuan Yun, Di Wu, Xin Wang
期刊:KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 :3.300
引用产品:PM150910
-
IL-17A Promotes the Migration, Invasion and the EMT Process of Lung Cancer Accompanied by NLRP3 Activation(2022/10/30)
作者:Wenping Liu, Miaomiao Xin, Qing Li
期刊:Biomed Research International
影响因子 :3.246
-
Circ_0026359 induces HOXA9 to regulate gastric cancer malignant progression through miR-140-3p(2022/08/22)
作者:Shuirong Lu, Jinlai Lu, Lang Liu
期刊:Applied Biological Chemistry
DOI:10.1186/s13765-022-00726-6
影响因子 :3.200
-
Hsa_circ_0032389 Enhances Proliferation and Migration in PDGF-BB-Induced Human Aortic Vascular Smooth Muscle Cells(2024/02/20)
作者:Haiyun Qian, Shengwei Ma, Qian Zhou
期刊:Cardiovascular Toxicology
DOI:10.1007/s12012-024-09833-w
影响因子 :3.200
引用产品:PM150910
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pH-sensitive magnetic microcapsules for simultaneously controlled-releasing two drugs(2021/06/21)
作者:Liwen Tang, Ruiting Yang, Haifang Liu
期刊:International Journal of Polymeric Materials and Polymeric Biomaterials
DOI:10.1080/00914037.2021.1937161
影响因子 :3.200
-
Concomitant drugs-loaded microcapsules of roxithromycin and theophylline with pH-sensitive controlled-releasing properties(2019/04/12)
作者:You Zhou, Bining Qiu, Xueqiong Yin
期刊:International Journal of Polymeric Materials and Polymeric Biomaterials
DOI:10.1080/00914037.2019.1596917
影响因子 :3.200
-
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening(2023/02/07)
作者:Yicheng Ni, Zhongyuan Luo, Yixin Lv
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.02.014
影响因子 :3.100
-
The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer(2023/11/24)
作者:Xuan Zhang, Tao Wu, Rujia Qin
期刊:Frontiers in Bioscience-Landmark
影响因子 :3.100
引用产品:PM150910
-
Evaluation of hsa_circ_0000018/let-7f-5p/ FAM96A axis in lung adenocarcinoma progression(2023/11/23)
作者:Qi Li, Min Zhao, Dandan Hu
期刊:Cancer Biomarkers
影响因子 :3.100
引用产品:PM150910
-
Synthesis and evaluation of a 68Ga-labeled spermine derivative for tumor PET imaging(2024/04/26)
作者:Kaixin Qin, Dongmei Shi, Yuzhou Zheng
期刊:NUCLEAR MEDICINE AND BIOLOGY
DOI:10.1016/j.nucmedbio.2024.108915
影响因子 :3.100
引用产品:PM150910
-
Astragaloside IV regulates circ_0001615 and miR-873-5p/LASP1 axis to suppress colorectal cancer cell progression(2024/01/04)
作者:Pengfei Kong, Xuemei Tang, Fang Liu
期刊:Chemical Biology & Drug Design
影响因子 :3.000
引用产品:PM150910
-
Fatty acid metabolism-related molecular subtypes and a novel model for predicting prognosis in bladder cancer patients(2024/01/05)
作者:Wenting Su, Jiayin Chen, Jiangbo Sun
期刊:JOURNAL OF BIOSCIENCES
DOI:10.1007/s12038-023-00383-x
影响因子 :2.900
引用产品:PM150910
-
Expression pattern, tumor immune landscape, and prognostic value of N7‑methylguanosine regulators in bladder urothelial carcinoma(2023/03/10)
作者:Chi Zhang, Jiangnan Xia, Simiao Zhang
期刊:Oncology Letters
影响因子 :2.900
引用产品:PM150910
-
CircRNA PRH1-PRR4 stimulates RAB3D to regulate the malignant progression of NSCLC by sponging miR-877-5p(2022/01/25)
作者:Jun Ma, Quanxing Li, Yuling Li
期刊:Thoracic Cancer
影响因子 :2.900
-
Modulation of Vascular Smooth Muscle Cell Multiplication, Apoptosis, and Inflammatory Damage by miR-21 in Coronary Heart Disease(2021/11/27)
作者:Wei Liu, Yilin Li, Dongming Zhao
期刊:Computational and Mathematical Methods in Medicine
影响因子 :2.809
引用产品:PM150910
-
Metformin attenuates TGF-β1-induced pulmonary fibrosis through inhibition of transglutaminase 2 and subsequent TGF-β pathways(2020/06/03)
作者:Yubo Wang, Caiyu Lin, Rui Han
期刊:3 BIOTECH
DOI:10.1007/s13205-020-02278-2
影响因子 :2.800
-
Silencing of lncRNA MALAT1 inhibits cell cycle progression via androgen receptor signaling in prostate cancer cells(2019/1/7)
作者:Xiaofan Dai, Lingyun Liu, Zuowen Liang
期刊:Pathology Research And Practice
影响因子 :2.800
-
Transcription factor E2F3 activates CDC25B to regulate DNA damage and promote mitoxantrone resistance in stomach adenocarcinoma(2024/01/09)
作者:Xiaoming Pan, Chaobo Xu, Guoxiong Cheng
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08933-0
影响因子 :2.800
引用产品:PM150910
-
LncRNA RP11-521C20.3 Inhibits Cigarette Smoke Extract-Induced Apoptosis in A549 Cells by Targeting BMF Signaling(2023/04/21)
作者:Yong Zhong, Chuntao Li, Yaling Xiang
期刊:International Journal of Chronic Obstructive Pulmonary Disease
影响因子 :2.800
引用产品:PM150910
-
PKNOX2 suppresses lung cancer cell proliferation by inhibiting the PI3K/AKT/mTOR axis(2023/03/28)
作者:Minglei Song, Nan Zhang, Fumin Cao
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
引用产品:PM150910
-
Circ_0007422 Knockdown Inhibits Tumor Property and Immune Escape of Colorectal Cancer by Decreasing PDL1 Expression in a miR-1256-Dependent Manner(2024/01/22)
作者:Dian Yin, Li Yang, Xiu Feng
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-01040-2
影响因子 :2.600
引用产品:PM150910
-
Resveratrol Inhibits Colorectal Cancer Cell Tumor Property by Activating the miR-769-5p/MSI1 Pathway(2024/05/21)
作者:Hongchang Liu, Liangliang Zhang, Liangliang Hao
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-024-01167-w
影响因子 :2.600
引用产品:PM150910
-
Exosomal circKDM4A Induces CUL4B to Promote Prostate Cancer Cell Malignancy in a miR-338-3p-Dependent Manner(2022/08/05)
作者:Guangyi Huang, Zeping Jiang, Wuan Zhu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10251-2
影响因子 :2.400
引用产品:PM150910
-
Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者:Wenjing Lu, Zhigao Yu, Jun Liu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10312-6
影响因子 :2.400
引用产品:164210-50 CL-0016 CL-0094 CL-0298 CM-0016 CM-0094 CM-0298 PB180120 PM150110 PM150210 PM150910
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Vitamin B6 ameliorates acute pancreatitis by suppressing the caspase3 signaling pathway(2024/05/02)
作者:Heling Xu, Hongqin Yue, Haijue Ge
期刊:BMC GASTROENTEROLOGY
DOI:10.1186/s12876-024-03248-1
影响因子 :2.400
引用产品:PM150910
-
Depletion of circPDSS1 inhibits ITGA11 production to confer cisplatin sensitivity through miR-515-5p in gastric cancer(2022/12/09)
作者:Yongsen Wang, Shuting Tang, Lingling Li
期刊:JOURNAL OF CHEMOTHERAPY
DOI:10.1080/1120009X.2022.2151702
影响因子 :2.385
引用产品:PM150910
-
Anti-cancer effects of Coix seed extract through KCTD9-mediated ubiquitination of TOP2A in lung adenocarcinoma(2024/02/20)
作者:Jiuyang Jiang, Xue Li, Chun Zhang
期刊:Cell Division
DOI:10.1186/s13008-024-00112-2
影响因子 :2.300
引用产品:PM150910
-
Anlotinib Inhibits Cisplatin Resistance in Non-Small-Cell Lung Cancer Cells by Inhibiting MCL-1 Expression via MET/STAT3/Akt Pathway(2024/03/04)
作者:Lile Wang, Lu Xu, Shuhua Han
期刊:Canadian Respiratory Journal
影响因子 :2.200
引用产品:PM150910
-
Bioactive components and the molecular mechanism of Shengxian Decoction against lung adenocarcinoma based on network pharmacology and molecular docking(2023/12/15)
作者:Ruijiao Yuan, Kejuan Li, Qi Li
期刊:American Journal of Translational Research
DOI:PMID:38186989
影响因子 :2.200
引用产品:PM150910
-
Circular RNA circSDHC (hsa_circ_0015004) regulates tumor growth and angiogenesis via regulating centrosomal protein 55 expression in renal cell carcinoma(2022/10/01)
作者:Long Pei, Chunhui Dong, Yanchao Wang
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.130
引用产品:PM150910
-
Involvement of ZDHHC9 in lung adenocarcinoma: regulation of PD-L1 stability via palmitoylation(2023/03/31)
作者:Zhe Li, Da Jiang, Fengling Liu
期刊:IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI:10.1007/s11626-023-00755-5
影响因子 :2.100
-
Targeting Thbs1 reduces bladder remodeling caused by partial bladder outlet obstruction via the FGFR3/p-FGFR3 pathway(2023/12/18)
作者:Jun Long, Yafei Yang, Jin Yang
期刊:NEUROUROLOGY AND URODYNAMICS
影响因子 :2.000
引用产品:PM150910
-
Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p(2023/06/01)
作者:Kun Fang, Yibin Deng, Ping Yang
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000
引用产品:PM150910
-
Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis(2023/07/07)
作者:Guihong Zhang, Yongde Zhu, Yonghuang Tan
期刊:Journal of Cardiothoracic Surgery
DOI:10.1186/s13019-023-02332-z
影响因子 :1.600
引用产品:PM150910
-
GATA2/FGF21 Axis Regulates the Effects of High Glucose on the Apoptosis, Autophagy and Oxidative Stress of Human Umbilical Vein Endothelial Cell via PI3K/AKT/mTOR Pathway(2022/03/01)
作者:Jinyan Zheng, Xiaojiang Ma, Yimeng Zhou
期刊:Annals Of Clinical And Laboratory Science
DOI:PMID:35414507
影响因子 :0.800
-
circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway(2022/01/06)
作者:Yu Li, Guangle Qin, Jinyun Du
期刊:Journal of Healthcare Engineering
影响因子 :0.000
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