产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
| 名称 | GC-2spd(ts) (小鼠精母细胞) (STR鉴定正确) |
| 别称 | GC-2 |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:4-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The cells have lost their differentiation potential, and are currently arrested at a premeiotic stage. |
| 年龄（性别） | 雄性；6周龄 |
| 组织来源 | 精母细胞；SV40大T抗原转染 |
| 细胞类型 | 条件永生化细胞系 |
| 生物安全等级 | BSL-2 |
| 应用领域 | This cell line may be useful for the study of spermatogenesis. |
| 保藏机构 | ATCC; CRL-2196 BCRC; 60313 |
STR鉴定
-
STR位点信息
18-3 16,17 6-7 17 5-5 14,17,18,19 X-1 28 1-2 13,19 7-1 26.2,29 8-1 16 1-1 17 19-2 13 15-3 22.3 12-1 17 6-4 18 4-2 20.3 3-2 14 2-1 16 13-1 15.2,17.1
11-2 16 17-2 15 -
STR鉴定图
-
参考文献
-
The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis(2023/09/27)
作者：Zirun Jin, Yuzhuo Yang, Yalei Cao
期刊：Microbiome
DOI：10.1186/s40168-023-01659-y
影响因子 ：15.500
引用产品：CL-0593
-
Gut-Derived Exosomes Mediate the Microbiota Dysbiosis-Induced Spermatogenesis Impairment by Targeting Meioc in Mice(2024/03/25)
作者：Tong Chen, Boqi Zhang, Guitian He
期刊：Advanced Science
影响因子 ：15.100
引用产品：CL-0593
-
The necroptosis-mediated imbalance of mitochondrial dynamics is involved in DEHP-induced toxicity to immature testes via the PGAM5–DRP1 interaction(2024/02/15)
作者：Xiazhu Zhou, Yifan Hong, Jing Chen
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2024.123585
影响因子 ：8.900
引用产品：CL-0593
-
Roles of ferroptosis in type 1 diabetes induced spermatogenic dysfunction(2024/02/17)
作者：Yalei Cao, Zirun Jin, Yu Xi
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.02.006
影响因子 ：7.400
引用产品：CL-0593
-
The rare-earth yttrium induces cell apoptosis and autophagy in the male reproductive system through ROS-Ca2+-CamkII/Ampk axis(2023/07/20)
作者：Fangpeng Hou, Junyun Huang, Furong Qing
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115262
影响因子 ：6.800
-
X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity(2023/03/27)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：Genes & Diseases
DOI：10.1016/j.gendis.2023.02.030
影响因子 ：6.800
-
N-acetylcysteine rescues meiotic arrest during spermatogenesis in mice exposed to BDE-209(2023/02/18)
作者：Yu Wei, Wenfeng Geng, Taifa Zhang
期刊：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
DOI：10.1007/s11356-023-25874-0
影响因子 ：5.800
引用产品：CL-0593
-
Dapagliflozin ameliorates diabetes-induced spermatogenic dysfunction by modulating the adenosine metabolism along the gut microbiota-testis axis(2024/01/05)
作者：Zirun Jin, Yalei Cao, Qi Wen
期刊：Scientific Reports
DOI：10.1038/s41598-024-51224-2
影响因子 ：4.600
引用产品：CL-0593
-
BDE-209 induce spermatocytes arrest at early-pachytene stage during meiotic prophase I in mice(2021/12/20)
作者：Jinxia Zhai, Wenfeng Geng, Taifa Zhang
期刊：Toxicology
影响因子 ：4.500
引用产品：CL-0593
-
Curcumin attenuates diphenyl phosphate-induced apoptosis in GC-2spd(ts) cells through activated autophagy via the Nrf2/P53 pathway(2023/12/14)
作者：Lai Wei, Siwen Li, Yu Ma
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.500
引用产品：CL-0593
-
The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation(2023/08/26)
作者：Siwen Li, Lemei Liu, Gang Luo, Yu Yuan, Die Hu, Fang Xiao
期刊：FOOD AND CHEMICAL TOXICOLOGY
影响因子 ：4.300
-
Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway(2023/06/05)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：TOXICOLOGY IN VITRO
影响因子 ：3.200
FAQs
Q：{{item.question}}
A：
产品资料
识别码示意图
