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产品概述
| 名称 | GC-1 spg (小鼠精原细胞) (种属鉴定正确) |
| 别称 | GC-1spg; GC-1; GC1-SPG |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:4-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Type B spermatogonia were immortalized by transfection with pSV3-neo (a plasmid containing coding sequences for the SV40 large T antigen and neomycin resistance) |
| 年龄（性别） | 雄性；10日龄 |
| 组织来源 | 睾丸 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-2 |
| 保藏机构 | ATCC; CRL-2053 |
STR鉴定
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STR位点信息
18-3 17,19 6-7 12,13 5-5 14 X-1 25 1-2 13 7-1 29 8-1 15 1-1 10 19-2 11,12 15-3 20.3 12-1 20 6-4 16 4-2 19.3,20.3 3-2 14 2-1 9 13-1 16.2,17.2
11-2 15,17 17-2 13,14 -
STR鉴定图
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参考文献
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Gut-Derived Exosomes Mediate the Microbiota Dysbiosis-Induced Spermatogenesis Impairment by Targeting Meioc in Mice(2024/03/25)
作者：Tong Chen, Boqi Zhang, Guitian He
期刊：Advanced Science
影响因子 ：15.100
引用产品：CL-0600
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Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy(2023/03/20)
作者：Jun Wu, Fuming Deng, Xiangliang Tang
期刊：JOURNAL OF HAZARDOUS MATERIALS
DOI：10.1016/j.jhazmat.2023.131234
影响因子 ：13.600
引用产品：CL-0600
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Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation(2022/09/16)
作者：Junchao Qin, Tao Huang, Zixiang Wang
期刊：CELL DEATH AND DIFFERENTIATION
DOI：10.1038/s41418-022-01057-1
影响因子 ：12.400
引用产品：CL-0600
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The necroptosis-mediated imbalance of mitochondrial dynamics is involved in DEHP-induced toxicity to immature testes via the PGAM5–DRP1 interaction(2024/02/15)
作者：Xiazhu Zhou, Yifan Hong, Jing Chen
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2024.123585
影响因子 ：8.900
引用产品：CL-0600
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Wnt10a downregulation contributes to MEHP-induced disruption of self-renewal and differentiation balance and proliferation inhibition in GC-1 cells: Insights from multiple transcriptomic profiling(2023/06/24)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2023.122091
影响因子 ：8.900
引用产品：CL-0600
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The rare-earth yttrium induces cell apoptosis and autophagy in the male reproductive system through ROS-Ca2+-CamkII/Ampk axis(2023/07/20)
作者：Fangpeng Hou, Junyun Huang, Furong Qing
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115262
影响因子 ：6.800
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X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity(2023/03/27)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：Genes & Diseases
DOI：10.1016/j.gendis.2023.02.030
影响因子 ：6.800
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The protective effect of C-phycocyanin in male mice reproductive system(2022/01/28)
作者：Fanghao Yang, Xiaolei Dong, Guoxiang Liu
期刊：Food & Function
影响因子 ：6.100
引用产品：CL-0600
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Ferritinophagy-mediated ferroptosis of spermatogonia is involved in busulfan-induced oligospermia in the mice(2024/01/12)
作者：Jinyu Xu, Lianshuang Zhang, Yaru Si
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 ：5.100
引用产品：CL-0600
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Melatonin Ameliorates Diquat-Induced Testicular Toxicity via Reducing Oxidative Stress, Inhibiting Apoptosis, and Maintaining the Integrity of Blood-Testis Barrier in Mice(2023/02/08)
作者：Li Yang, Jianyong Cheng, Dejun Xu
期刊：Toxics
影响因子 ：4.600
引用产品：CL-0600
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Testicular dysfunction and “its recovery effect” after cadmium exposure(2024/04/12)
作者：Qi Zhang, YanLing Yang, Juan Liu
期刊：FOOD AND CHEMICAL TOXICOLOGY
影响因子 ：4.300
引用产品：CL-0600
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Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway(2023/06/05)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：TOXICOLOGY IN VITRO
影响因子 ：3.200
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Effect of Low Dietary Folate on Mouse Spermatogenesis and Spindle Assembly Checkpoint Dysfunction May Contribute to Folate Deficiency-Induced Chromosomal Instability in Cultured Mouse Spermatogonia(2023/06/08)
作者：Huanhuan Ren, Kaixian Wang, Zirui Liu
期刊：DNA AND CELL BIOLOGY
影响因子 ：3.100
引用产品：CL-0600
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The mechanism analysis using PI3K/AKT pathway for the effects of levocarnitine in the treatment of spermatogenic dysfunction(2021/10/28)
作者：Jisheng Wang, Binghao Bao, Fanchao Meng
期刊：Andrologia
影响因子 ：2.532
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