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  • 小鼠骨髓间充质干细胞
  • 小鼠骨髓间充质干细胞
  • 小鼠骨髓间充质干细胞
  • 小鼠骨髓间充质干细胞

小鼠骨髓间充质干细胞
Mouse Bone Marrow Mesenchymal Stem Cells

货号:CP-M131

规格:5×10⁵Cells/T25培养瓶

价格: ¥3380

培养基货号: CM-M131

数量: - +
  • 小鼠骨髓间充质干细胞
  • 小鼠骨髓间充质干细胞
  • 小鼠骨髓间充质干细胞
  • 小鼠骨髓间充质干细胞
产品概述

小鼠骨髓间充质干细胞

Cat NO.: CP-M131

  1. 产品名称:小鼠骨髓间充质干细胞

  2. 英文简称:BMSCs,MSCs

  3. 组织来源:骨髓

  4. 产品规格:5×105cells/T25细胞培养瓶

  5. 细胞简介:

    小鼠骨髓间充质干细胞(BMSC)分离自骨髓;骨髓是机体的造血组织,位于身体的许多骨骼内。成年动物的骨髓分两种:红骨髓和黄骨髓。红骨髓能制造红细胞、血小板和各种白细胞。血小板有止血作用,白细胞能杀灭与抑制各种病原体,包括细菌、病毒等;某些淋巴细胞能制造抗体。因此,骨髓不但是造血器官,它还是重要的免疫器官。骨髓是存在于长骨(如肱骨、股骨)的骨髓腔和扁平骨(如髂骨)的稀松骨质间的网眼中,是一种海绵状的组织,能产生血细胞的骨髓略呈红色,称为红骨髓。出生时,红骨髓充满全身骨髓腔,随着年龄增大,脂肪细胞增多,相当部分红骨髓被黄骨髓取代,最后几乎只有扁平骨骨髓腔中有红骨髓。骨髓基质系统内存在的骨髓间充质干细胞是一种除造血干细胞以外的、具有高度自我更新能力和多向分化潜能的干细胞,可以向骨、软骨、肌组织、皮肤、脂肪、神经等多种组织分化,因此可以作为组织工程中的种子细胞。在骨髓中,BMSC占骨髓有核细胞总数的0.001%-0.1%,含量极低。骨髓间充质干细胞的体外培养条件要求较高,在培养过程中,受贴壁时间、种植密度、血清含量、培养温度和培养基pH值等条件的影响。

  6. 方法简介:

    普诺赛实验室分离的小鼠骨髓间充质干细胞采用冲洗骨髓、密度梯度离心、差速贴壁法结合培养基筛选制备而来,细胞总量约为5×10⁵cells/瓶。

  7. 质量检测:

    普诺赛实验室分离的小鼠骨髓间充质干细胞经CD29或CD44免疫荧光鉴定,纯度可达90%以上,且不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌等。

  8. 培养信息:

    包被条件
    培养基含FBS、生长添加剂、Penicillin、Streptomycin等
    产品货号CM-M131
    换液频率每2-3天换液一次
    生长特性贴壁
    细胞形态成纤维细胞样
    传代特性可传2-3代
    消化液0.25%胰蛋白酶
    培养条件气相:空气,95%;CO2,5%

    小鼠骨髓间充质干细胞体外培养周期有限;建议使用普诺赛配套的专用生长培养基及正确的操作方法来培养,以此保证该细胞的最佳培养状态。

参考文献
文献列表
  • Injectable and Microporous Microgel Assembly with Sequential Bioactive Factor Release for the Endogenous Repair of Nucleus Pulposus(2024/01/16)

    作者:Huitong Luo, Zetao Wang, Fanglei Yu

    期刊:ADVANCED FUNCTIONAL MATERIALS

    DOI:10.1002/adfm.202315592

    影响因子 :19.000

    引用产品:CP-M131

  • Bioinspired Nanovesicles Convert the Skeletal Endothelium-Associated Secretory Phenotype to Treat Osteoporosis(2022/07/08)

    作者:Yongzhi Cui, Zhongying Li, Yuanyuan Guo

    期刊:ACS Nano

    DOI:10.1021/acsnano.2c03781

    影响因子 :17.100

    引用产品:CP-M131

  • Chitosan based photothermal scaffold fighting against bone tumor-related complications: Recurrence, infection, and defects(2022/10/26)

    作者:Yao Zhao, Xu Peng, Xiaoyang Xu

    期刊:CARBOHYDRATE POLYMERS

    DOI:10.1016/j.carbpol.2022.120264

    影响因子 :11.200

    引用产品:CL-0157 CL-0492 CP-M131

  • Decellularized extracellular matrix and mesenchymal stem cells promote recovery in traumatic brain injury by synergistically enhancing neurogenesis and attenuating neuroinflammation(2022/10/01)

    作者:Xuewei Zhang, Bixue Wang, Hua Hong

    期刊:Journal of Materials Science & Technology

    DOI:10.1016/j.jmst.2022.08.028

    影响因子 :10.900

    引用产品:CL-0493 CP-M131

  • A spatiotemporal drug release scaffold with antibiosis and bone regeneration for osteomyelitis(2023/01/24)

    作者:Shengda Wu, Yang Shuai, Guowen Qian

    期刊:Journal of Advanced Research

    DOI:10.1016/j.jare.2023.01.019

    影响因子 :10.700

    引用产品:CP-M131

  • Fabrication of Biofunctionalized Surfaces for Osteo-regeneration by Directional Seeding of Lactoferrin at the Solid-Liquid Interface(2022/08/04)

    作者:Xiaokang Na, Xianfu Chen, Xianbing Xu

    期刊:Materials Today Nano

    DOI:10.1016/j.mtnano.2022.100250

    影响因子 :10.300

    引用产品:CP-M131

  • Ångstrom-scale gold particles loaded with alendronate via alpha-lipoic acid alleviate bone loss in osteoporotic mice(2024/04/30)

    作者:Weihang Gao, Jiaojiao Li, Jingyu Shi

    期刊:JOURNAL OF NANOBIOTECHNOLOGY

    DOI:10.1186/s12951-024-02466-9

    影响因子 :10.200

    引用产品:CP-M131

  • Decellularized extracellular matrix enriched with GDNF enhances neurogenesis and remyelination for improved motor recovery after spinal cord injury(2024/04/16)

    作者:Jiashang Liu, Ruijia Yan, Bixue Wang

    期刊:Acta Biomaterialia

    DOI:10.1016/j.actbio.2024.04.015

    影响因子 :9.700

    引用产品:CP-M131

  • An injectable CS-hydrogel incorporating TPGS for cartilage repair(2024/03/31)

    作者:Qingqiang Tu, Dong Jiang, Rongcheng Hu

    期刊:MATERIALS & DESIGN

    DOI:10.1016/j.matdes.2024.112894

    影响因子 :8.400

    引用产品:CP-M131

  • Mesenchymal stem cells overexpressing XIST induce macrophage M2 polarization and improve neural stem cell homeostatic microenvironment, alleviating spinal cord injury(2024/01/10)

    作者:Dan Zhu, Tie Peng, Zhenwang Zhang

    期刊:Journal of Tissue Engineering

    DOI:10.1177/20417314231219280

    影响因子 :8.200

    引用产品:CP-M131

  • Targeted Delivery of Mesenchymal Stem Cell-Derived Bioinspired Exosome-Mimetic Nanovesicles with Platelet Membrane Fusion for Atherosclerotic Treatment(2024/03/13)

    作者:Yu Jiang, Miao Yu, Zhifeng Song

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S452824

    影响因子 :8.000

    引用产品:CP-M131

  • MicroRNA let-7g links foam cell formation and adipogenic differentiation: A key regulator of Paeonol treating atherosclerosis-osteoporosis(2024/02/11)

    作者:Jinjin Yan, Yulong Yang, Yarong Liu

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2024.155447

    影响因子 :7.900

    引用产品:CP-M131

  • TFAM-Mediated mitochondrial transfer of MSCs improved the permeability barrier in sepsis-associated acute lung injury(2023/04/15)

    作者:Feng Zhang, Xinglong Zheng, Fengzhi Zhao

    期刊:APOPTOSIS

    DOI:10.1007/s10495-023-01847-z

    影响因子 :7.200

    引用产品:CM-M001 CP-M001 CP-M131

  • Isoliquiritin treatment of osteoporosis by promoting osteogenic differentiation and autophagy of bone marrow mesenchymal stem cells(2023/10/19)

    作者:Zhikang Su, Ding Chen, Jiangyon Huang

    期刊:PHYTOTHERAPY RESEARCH

    DOI:10.1002/ptr.8032

    影响因子 :7.200

    引用产品:CP-M131

  • Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles(2022/12/26)

    作者:Jun Deng, Hui Ke

    期刊:OncoImmunology

    DOI:10.1080/2162402X.2022.2152635

    影响因子 :7.200

    引用产品:CL-0120 CP-M131 PB180323 PM150110 PM150210

  • A Synergistic Therapeutic Nano Eyedrop for Dry Eye Disease Based on Ascorbic Acid-Coupled Exosomes(2022/12/16)

    作者:Fang Ma, Jing Feng, Xi Liu

    期刊:Nanoscale

    DOI:10.1039/D2NR05178H

    影响因子 :6.700

    引用产品:CP-M131

  • Topical Application of Butyl Flufenamate Ointment Promotes Cranial Defect Healing in Mice by Inducing BMP2 Secretion in Skin Mesenchymal Stem Cells(2022/11/15)

    作者:Fan Yang, Xuenan Liu, Donghao Wei, Yuan Zhu, Feilong Wang, Xuejiao Liu, Fanyu Yan, Xiao Zhang, Yunsong Liu

    期刊:Cells

    DOI:10.3390/cells11223620

    影响因子 :6.000

    引用产品:CP-M131

  • 3WJ RNA Nanoparticles-Aptamer Functionalized Exosomes From M2 Macrophages Target BMSCs to Promote the Healing of Bone Fractures(2023/09/22)

    作者:Jiali Shou, Shuyi Li, Wenzhe Shi

    期刊:Stem Cells Translational Medicine

    DOI:10.1093/stcltm/szad052

    影响因子 :6.000

    引用产品:CL-0190 CP-M131

  • Bone-Differentiation-Associated Circ-Spen Regulates Death of Mouse Bone Marrow Mesenchymal Stem Cells by Inhibiting Apoptosis and Promoting Autophagy(2024/03/06)

    作者:Ziwen Liang, Bingjie Luo, Bojia Peng

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms25053034

    影响因子 :5.600

    引用产品:CP-M131

  • Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head(2023/07/21)

    作者:Yannan Cheng, Hui Chen, Ping Duan

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.110639

    影响因子 :5.600

    引用产品:CL-0190 CM-0190 CP-M131

  • Exosomal miR-127-5p from BMSCs alleviated sepsis-related acute lung injury by inhibiting neutrophil extracellular trap formation(2023/08/07)

    作者:Xinglong Zheng, Feng Zhang, Fengzhi Zhao

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.110759

    影响因子 :5.600

    引用产品:CP-M131

  • Exosomal miR-223-3p from bone marrow mesenchymal stem cells targets HDAC2 to downregulate STAT3 phosphorylation to alleviate HBx-induced ferroptosis in podocytes(2024/02/20)

    作者:Yueqi Chen, Yongzheng Hu, Wei Jiang

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2024.1327149

    影响因子 :5.600

    引用产品:CP-M131

  • Zeolitic Imidazolate Frameworks Serve as an Interface Layer for Designing Bifunctional Bone Scaffolds with Antibacterial and Osteogenic Performance(2023/10/25)

    作者:Jingxi Huang, Chen Cheng, Youwen Yang

    期刊:Nanomaterials

    DOI:10.3390/nano13212828

    影响因子 :5.300

    引用产品:CP-M131

  • Intensified cross-linking dramatically improved mechanical properties of hydroxyapatite and cellulose composites for repairing bone segmental defects(2024/02/07)

    作者:Qingyou Liang, Jie Dong, Jian Ren

    期刊:Materials Advances

    DOI:10.1039/D3MA00974B

    影响因子 :5.000

    引用产品:CP-M131

  • Nano−/micro-scaled hydroxyapatite ceramic construction and the regulation of immune-associated osteogenic differentiation(2023/09/08)

    作者:Shijia Fu, Huishan Li, Yue Wu

    期刊:JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

    DOI:10.1002/jbm.a.37606

    影响因子 :4.900

    引用产品:CP-M131

  • Preparation and characterization of a novel composite acellular matrix/hyaluronic acid thermosensitive hydrogel for interstitial cystitis/bladder pain syndrome(2023/11/16)

    作者:Wei Guo, Haichao Liu, Jiaxing Zhang

    期刊:JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

    DOI:10.1002/jbm.a.37643

    影响因子 :4.900

    引用产品:CP-M131

  • Total flavonoids of Rhizoma drynariae improves tendon-bone healing for anterior cruciate ligament reconstruction in mice and promotes the osteogenic differentiation of bone mesenchymal stem cells by the ERR1/2-Gga1-TGF-β/MAPK pathway(2023/09/04)

    作者:Lei Han, Canfeng Wang, Tuo Wang

    期刊:ENVIRONMENTAL TOXICOLOGY

    DOI:10.1002/tox.23955

    影响因子 :4.500

    引用产品:CP-M131

  • Doxorubicin-Induced Cardiotoxicity May Be Alleviated by Bone Marrow Mesenchymal Stem Cell-Derived Exosomal lncRNA via Inhibiting Inflammation(2022/08/06)

    作者:Chao Tian, Yanyan Yang, Bing Li

    期刊:Journal of Inflammation Research

    DOI:10.2147/JIR.S358471

    影响因子 :4.500

    引用产品:CP-M131

  • RIOK3 potentially regulates osteogenesis-related pathways in ankylosing spondylitis and the differentiation of bone marrow mesenchymal stem cells(2023/10/20)

    作者:Hexiang Zong, Yaqian Liu, Xile Wang

    期刊:GENOMICS

    DOI:10.1016/j.ygeno.2023.110730

    影响因子 :4.400

    引用产品:CP-M131

  • Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response(2023/07/26)

    作者:Ruixi Luo, Yaqiong Wei, Peng Chen

    期刊:Stem Cells International

    DOI:10.1155/2023/4483776

    影响因子 :4.300

    引用产品:CP-M131

  • FAIM Enhances the Efficacy of Mesenchymal Stem Cell Transplantation by Inhibiting JNK-Induced c-FLIP Ubiquitination and Degradation(2022/09/30)

    作者:Jinyong Chen, Feng Liu, Wangxing Hu

    期刊:Stem Cells International

    DOI:10.1155/2022/3705637

    影响因子 :4.300

    引用产品:CP-M131

  • Exosomes derived from bone marrow mesenchymal stem cells attenuate NLRP3 related pyroptosis in autoimmune premature ovarian insufficiency via NF-κB pathway(2024/01/09)

    作者:Jiaxin Xie, Yutao Yang, Aiping Zhuo

    期刊:REPRODUCTIVE BIOMEDICINE ONLINE

    DOI:10.1016/j.rbmo.2024.103814

    影响因子 :4.000

    引用产品:CP-M131

  • miR-21-loaded BMSC-derived Exosomes repair ovarian function of autoimmune premature ovarian insufficiency by targeting MSX1(2024/01/09)

    作者:Yutao Yang, Lichao Tang, Yuanling Xiao

    期刊:REPRODUCTIVE BIOMEDICINE ONLINE

    DOI:10.1016/j.rbmo.2024.103815

    影响因子 :4.000

    引用产品:CP-M131

  • Poly(I:C)-Induced Mesenchymal Stem Cells Protect the Kidney Against Ischemia/Reperfusion Injury via the TLR3/PI3K Pathway(2021/11/25)

    作者:Tian Chen, Yamei Jiang, Shihao Xu

    期刊:Frontiers in Medicine

    DOI:10.3389/fmed.2021.755849

    影响因子 :3.900

    引用产品:CP-M131

  • Bone marrow-mesenchymal stem cell-derived exosomal microRNA-141 targets PTEN and activates β-catenin to alleviate myocardial injury in septic mice(2021/07/26)

    作者:Yongju Pei, Shutang Xie, Jiang Li

    期刊:Immunopharmacology And Immunotoxicology

    DOI:10.1080/08923973.2021.1955920

    影响因子 :3.300

    引用产品:CP-M073 CP-M131

  • MiR-145 enriched exosomes derived from bone marrow-derived mesenchymal stem cells protects against cerebral ischemia-reperfusion injury through downregulation of FOXO1(2022/09/27)

    作者:Hai Zhou, Jing Zhou, Hongwei Teng

    期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

    DOI:10.1016/j.bbrc.2022.09.089

    影响因子 :3.100

    引用产品:CL-0493 CP-M131

  • Baicalin regulates the development of pediatric asthma via upregulating microRNA-103 and mediating the TLR4/NF-κB pathway(2021/3/17)

    作者:Chuanhua Zhai, Debing Wang

    期刊:Journal Of Receptors And Signal Transduction

    DOI:10.1080/10799893.2021.1900865

    影响因子 :2.800

    引用产品:CM-M131 CP-M131

  • Study on the mechanism of NLRP3 effect on the skeleton of de-ovalized mice(2023/06/10)

    作者:Chenchen Yang, Bing Song, Lixia Han

    期刊:Biochemistry and Biophysics Reports

    DOI:10.1016/j.bbrep.2023.101496

    影响因子 :2.700

    引用产品:164210 164210-50 CP-M131 PB180120 PM150421

  • Dihydroartemisinin Promoted Bone Marrow Mesenchymal Stem Cell Homing and Suppressed Inflammation and Oxidative Stress against Prostate Injury in Chronic Bacterial Prostatitis Mice Model(2021/12/15)

    作者:Shen Li, Yongzhang Li, Xiaozhe Su

    期刊:Evidence-based Complementary and Alternative Medicine

    DOI:10.1155/2021/1829736

    影响因子 :2.650

    引用产品:CP-M131

  • Identification of differentially expressed autophagy genes associated with osteogenic differentiation in human bone marrow mesenchymal stem cells(2022/08/15)

    作者:Yibo Xu, Zhimeng Wang, Yakang Wang

    期刊:American Journal of Translational Research

    DOI:PMID:36105058

    影响因子 :2.200

    引用产品:CP-M131

  • A study of the role of myeloid-derived growth factor on acute lung injury in vitro and In vivo(2023/06/27)

    作者:Wenhui Gong, Shi Jiang, Jianbo Wang

    期刊:European Journal of Inflammation

    DOI:10.1177/1721727X231185390

    影响因子 :0.700

    引用产品:CP-M131

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