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![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0492-1-1.jpg)
![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0492-1-2.jpg)
![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0492-1-3.jpg)
![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0492-1-4.jpg)
![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0492-1-5.jpg)
![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0492-1-6.jpg)
![MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确)](/Public/upfile/pic/product/cell-line-new.jpg)
产品概述
| 名称 | MNNG/HOS Cl #5 [R-1059-D] (人骨肉瘤细胞) (STR鉴定正确) |
| 别称 | MNNG/HOS; MNNG-HOS; HOS-MNNG; MNNGHOS; MNNG-HOS (Cl#5) ; MNNG/HOS Clone F-5; MNNG; R-1059-D; TE85; TE-85; HOS-TE85; Hos TE-85; HOS TE 85; HOS TE85; HOS (TE85) ; HOS (TE85) ; HOS (TE85, Clone F5) ; MNNG-HOS (TE 85, clone F-5) ; HOS-Te85; TE 85.T; TE 85 ClF-5; TE-85 clone 5 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | MNNG/HOS Cl #5 [R-1059-D]细胞是HOS经0.01mcg/ml MNNG(一种致癌的亚硝胺)转化而来。MNNG/HOS Cl #5 [R-1059-D]细胞饱和浓度高，在软琼脂中的克隆形成率高，并能在裸鼠中成瘤。 |
| 年龄（性别） | 女性；13岁 |
| 组织来源 | 骨；骨肉瘤 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肉瘤细胞 |
| 生物安全等级 | BSL-1 |
| 保藏机构 | ATCC; CRL-1547 ECACC; 87070201 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 24,25 D3S1358 15 D5S818 13 D7S820 11,12 D8S1179 11,14 D13S317 12 D16S539 10,13 D18S51 14 D19S433 13 D21S11 31.2 FGA 24 PentaD 9,10 PentaE 7,12 TH01 6 TPOX 8,11 vWA 18 D6S1043 18 D12S391 20 D2S441 10 -
STR鉴定图
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参考文献
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Chitosan based photothermal scaffold fighting against bone tumor-related complications: Recurrence, infection, and defects(2022/10/26)
作者：Yao Zhao, Xu Peng, Xiaoyang Xu
期刊：CARBOHYDRATE POLYMERS
DOI：10.1016/j.carbpol.2022.120264
影响因子 ：11.200
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Engineered biomimetic nanoreactor for synergistic photodynamic-chemotherapy against hypoxic tumor(2022/09/22)
作者：Haoyu Guo, Lutong Wang, Wei Wu
期刊：JOURNAL OF CONTROLLED RELEASE
DOI：10.1016/j.jconrel.2022.09.020
影响因子 ：10.800
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A mitochondria-related signature for predicting immune microenvironment and therapeutic response in osteosarcoma(2022/12/01)
作者：Lina Zhang, Song Wu, Junjie Huang
期刊：Frontiers in Oncology
影响因子 ：5.738
引用产品：CL-0492
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2-Hydroxy-3-methylanthraquinone inhibits homologous recombination repair in osteosarcoma through the MYC-CHK1-RAD51 axis(2023/01/30)
作者：Doudou Jing, Xuanzuo Chen, Zhenhao Zhang
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-023-00611-y
影响因子 ：5.700
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A ferroptosis-related gene signature associated with immune landscape and therapeutic response in osteosarcoma.(2022/11/11)
作者：Xinxing Wang, Guang Xia, Shilang Xiao, Song Wu, Lina Zhang, Junjie Huang, Wenxiu Zhang, Xu Cao, Image_1.tif, Image_2.tif, Image_3.tif, Image_4.tif, Image_5.tif, Image_6.tif, Image_7.tif, DataSheet_1.csv, DataSheet_2.csv, DataSheet_3.csv, DataSheet_4.
期刊：Frontiers in Oncology
影响因子 ：4.700
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PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway(2023/12/09)
作者：Long Fang, Baolong Wang, Zengkun Yang
期刊：Scientific Reports
DOI：10.1038/s41598-023-49295-8
影响因子 ：4.600
引用产品：CL-0492
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Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway(2023/03/05)
作者：Xu Cai, Shaihong Zhu
期刊：Genomics
DOI：10.1016/j.ygeno.2023.110595
影响因子 ：4.400
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Identification of an EMT-related gene-based prognostic signature in osteosarcoma(2023/04/27)
作者：Haoli Gong, Ye Tao, Sheng Xiao
期刊：Cancer Medicine
影响因子 ：4.000
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A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction(2023/06/07)
作者：Junwei Pan, Ming Liu, Xiaozong Duan
期刊：PLoS One
DOI：10.1371/journal.pone.0286422
影响因子 ：3.700
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Disulfidptosis-related PABPC3 promotes tumor progression and inhibits immune activity in osteosarcoma(2023/12/07)
作者：Yangbo Cao, Song Wu, Yishan Gu
期刊：JOURNAL OF GENE MEDICINE
DOI：10.1002/jgm.3641
影响因子 ：3.500
引用产品：CL-0492
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Diverse cell death patterns-related signature for predicting prognosis and drug sensitivity of osteosarcoma patients(2023/10/20)
作者：Yanbin Shi, Song Wu, Xiaolin Zhang
期刊：JOURNAL OF GENE MEDICINE
DOI：10.1002/jgm.3613
影响因子 ：3.500
引用产品：CL-0492
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Circular RNA circ_0096041 promotes osteosarcoma cell proliferation and migration via sponging miR-556-5p and regulating LIN28A expression(2024/02/29)
作者：Fulin Zhou, Hao Wu, Zhen Yin
期刊：CELLULAR AND MOLECULAR BIOLOGY
影响因子 ：1.600
引用产品：CL-0492
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