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产品概述
| 名称 | 769-P (人肾细胞腺癌细胞) (STR鉴定正确) |
| 别称 | 769P; 769-p |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | 769-P细胞来源于原发性透明细胞腺癌；769-P细胞呈边界不清楚的球形、高核质比、有微绒毛和桥粒；769-P细胞可以在软琼脂中生长。 |
| 年龄（性别） | 女性；63岁 |
| 组织来源 | 器官：肾；疾病：肾透明细胞腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肾癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~35 hours |
| 致瘤性 | Yes, forms colonies in soft agar.Yes, forms tumors in immunosuppressed hamsters.Yes, forms tumors in nude mice. |
| 保藏机构 | ATCC; CRL-1933 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 18 D3S1358 16 D5S818 12 D7S820 10,11 D8S1179 12,16 D13S317 10,14 D16S539 9,13 D18S51 14,17 D19S433 14,15 D21S11 28,30 FGA 20,22 PentaD 12,16 PentaE 7,18 TH01 6,9.3 TPOX 8,11 vWA 18 D6S1043 11,14 D12S391 18 D2S441 11,14 -
STR鉴定图
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参考文献
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TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3(2024/05/22)
作者：Qi Zhang, Yong Li, Qing Zhu
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06741-3
影响因子 ：9.000
引用产品：CL-0009
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Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma(2022/09/30)
作者：Liangmin Fu, Jiahao Bao, Jinhui Li
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2022.1021935
影响因子 ：8.786
引用产品：CL-0009
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Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells(2024/03/30)
作者：Ziyao Li, Ye Tian, Huafeng Zong
期刊：APOPTOSIS
DOI：10.1007/s10495-024-01953-6
影响因子 ：7.200
引用产品：CL-0009
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma(2023/03/15)
作者：Lin Zhang, Bo Wu, Dongwen Wang
期刊：American Journal of Cancer Research
DOI：PMID:37034217
影响因子 ：5.300
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Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function(2023/07/06)
作者：Zhang Jichi, Wang Yujie, Ma Jun, Aimudula Ainiwaer
期刊：Frontiers in Oncology
影响因子 ：4.700
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Low ACADM expression predicts poor prognosis and suppressive tumor microenvironment in clear cell renal cell carcinoma(2024/04/25)
作者：Libin Zhou, Min Yin, Fei Guo
期刊：Scientific Reports
DOI：10.1038/s41598-024-59746-5
影响因子 ：4.600
引用产品：CL-0009
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Upregulation of Metallothionein 1 G (MT1G) Negatively Regulates Ferroptosis in Clear Cell Renal Cell Carcinoma by Reducing Glutathione Consumption(2022/09/27)
作者：Wu Zhang, Min Luo, Bingrui Xiong
期刊：Journal of Oncology
影响因子 ：4.501
引用产品：CL-0009
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ROCK2-RNA interaction map reveals multiple biological mechanisms underlying tumor progression in renal cell carcinoma(2023/07/07)
作者：Zhengdong Hong, Xuexin Chen, Lei Wang
期刊：Human Cell
DOI：10.1007/s13577-023-00947-x
影响因子 ：4.300
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The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma(2023/08/29)
作者：Ziqi Zhou, Xi Lv, Shibo Liu
期刊：Human Cell
DOI：10.1007/s13577-023-00973-9
影响因子 ：4.300
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TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT(2020/3/4)
作者：Mengya Zhong, Maoshu Zhu, Yu Liu
期刊：Journal of Cancer
影响因子 ：3.900
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LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability(2024/02/01)
作者：Hao Li, Xu Han, Liang Song
期刊：GENE
DOI：10.1016/j.gene.2024.148232
影响因子 ：3.500
引用产品：CL-0009
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway(2023/01/02)
作者：Zhechuan Zhang, Yuanfeng Zhang, Ronggui Zhang
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-022-01926-2
影响因子 ：3.400
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Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis(2024/05/11)
作者：Bin Zheng, Xue Jiang, Yaqing Liu
期刊：Discover Oncology
DOI：10.1007/s12672-024-01018-9
影响因子 ：2.200
引用产品：CL-0009
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis(2022/09/01)
作者：Sheng Xue, Hanxu Guo, Shibo Wei
期刊：Translational Andrology and Urology
影响因子 ：2.000
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CircSCNN1A inhibits the proliferation, migration and invasion of renal cell carcinoma cells by decreasing CLDN8 expression through miR-590-5p(2024/05/19)
作者：Tingting Guo, Wanjuan Xiong, Chong Liu
期刊：GENESIS
影响因子 ：1.500
引用产品：CL-0009
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