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产品概述
名称 | J82 (人膀胱移行细胞癌) (STR鉴定正确) |
别称 | J-82; J 82; J82COT; J82 COT |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | J82细胞源自一名58岁患有膀胱移行细胞癌的白人男性。J82细胞内无桥粒,有大量粗面内质网及突出绒毛,可表达ras基因。 |
年龄(性别) | 男性;58岁 |
组织来源 | 器官:膀胱;疾病:移行细胞癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 膀胱癌细胞 |
生物安全等级 | BSL-1 |
致瘤性 | Yes, in nude mice. |
抗原表达情况 | HLA A2, Aw32, B5, B12, Cw5; Blood Type A |
保藏机构 | ATCC; HTB-1 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 19 D3S1358 16,18 D5S818 12,13 D7S820 9,11 D8S1179 8,13 D13S317 10,12 D16S539 11,12 D18S51 10,12 D19S433 12,13 D21S11 30,31 FGA 20,24 PentaD 9,13 PentaE 12,15 TH01 9.3 TPOX 11,12 vWA 17,18 D6S1043 19 D12S391 24 D2S441 10,13 -
STR鉴定图
参考文献
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WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity(2023/01/07)
作者:Xiaosong Wei, Beibei Wang, Zixin Wu
期刊:CANCER LETTERS
DOI:10.1016/j.canlet.2023.216058
影响因子 :9.700
引用产品:CL-0002 CL-0125 CL-0222 CL-0227 CL-0463 CL-0628 PM150410 PM150710 PM150910 PM151010
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EFEMP2 suppresses epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human bladder cancer(2019/08/08)
作者:Qiang Zhou, Song Chen, Mengxin Lu
期刊:International Journal of Biological Sciences
影响因子 :9.200
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Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer(2022/11/17)
作者:Ren, Jiannan, Yu, Haixin, Li, Wei, Jin, Xin, Yan, Bin
期刊:BRITISH JOURNAL OF CANCER
DOI:10.1038/s41416-022-02058-0
影响因子 :8.800
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Transcriptomic insights into UTUC: role of inflammatory fibrosis and potential for personalized treatment(2024/01/05)
作者:Keqiang Li, Zhenlin Huang, Guoqing Xie
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04815-y
影响因子 :7.400
引用产品:CL-0125
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miR-4324-RACGAP1-STAT3-ESR1 feedback loop inhibits proliferation and metastasis of bladder cancer(2019/1/12)
作者:Qiangqiang Ge, Mengxin Lu, Lingao Ju
期刊:International Journal Of Cancer
影响因子 :6.400
引用产品:CL-0125
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Transcriptomic profiling and risk assessment in bladder cancer: Insights from copper death-related genes(2024/05/27)
作者:Xu Wang, Long Jin, Xiaoyu Zhang
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111237
影响因子 :4.800
引用产品:CL-0125
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POLR3G promotes EMT via PI3K/AKT signaling pathway in bladder cancer(2023/11/07)
作者:Hualin Chen, Lin Ma, Wenjie Yang
期刊:FASEB JOURNAL
影响因子 :4.800
引用产品:CL-0125
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The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis(2022/11/21)
作者:Jiani He, Changming Dong, Hao Zhang, Yuanjun Jiang, Tao Liu, Xiaojun Man
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2022.110527
影响因子 :4.800
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CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis(2024/01/01)
作者:Peng Zhang, Qian Yang, Xulong Chen
期刊:Journal of Cancer
影响因子 :3.900
引用产品:CL-0125
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MiR-34a-5p/PD-L1 axis regulates cisplatin chemoresistance of ovarian cancer cells(2019/12/26)
作者:Y Zuo, W Zheng, J Liu
期刊:Neoplasma
DOI:10.4149/neo_2019_190202N106
影响因子 :3.409
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PC4 promotes bladder cancer progression and stemness by directly interacting with Sp1 to transcriptionally activate the Wnt5a/β-catenin pathway(2024/05/26)
作者:Benhuang Yan, Peng Luo, Heping Qiu
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.800
引用产品:CL-0125
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