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产品概述
| 名称 | SV-HUC-1 (人输尿管上皮永生化细胞) (STR鉴定正确) |
| 别称 | HUC-1; SV-HUC; SVHUC |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 该细胞较难消化，注意延长消化时间，消化到细胞收缩变圆，轻拍培养瓶侧边，细胞可以滑落方可终止消化。 |
| 背景描述 | SV-HUC-1细胞是正常输尿管组织用SV40病毒转染建株的。反复用非洲绿猴肾细胞平板测试检测传染性SV40的生成，结果都呈阴性；SV-HUC-1细胞在胁迫(如曝露于化学试剂)下可能激活病毒。 |
| 年龄（性别） | 男性；11岁 |
| 组织来源 | 输尿管，输尿管上皮 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-2 |
| 致瘤性 | No, nude mice. |
| 基因表达情况 | uroepithelial keratins; SV40 T antigen |
| 保藏机构 | ATCC; CRL-9520 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 17 D3S1358 14,17 D5S818 12,14 D7S820 10,11 D8S1179 14,16 D13S317 12,13 D16S539 11 D18S51 15,16 D19S433 14 D21S11 29,30 FGA 21,22 PentaD 13 PentaE 10,20 TH01 9,9.3 TPOX 8,10 vWA 14 D6S1043 11,13 D12S391 18 D2S441 10,13 -
STR鉴定图
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参考文献
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Subcellular Nanobionic Liposome with High Zeta Potential Enhances Intravesical Adhesion and Drug Delivery(2024/01/22)
作者：Huifang Du, Haiyan Yin, Yinhua Qin
期刊：ACS Nano
影响因子 ：17.100
引用产品：CL-0222
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The alternation of halobenzoquinone disinfection byproduct on toxicogenomics of DNA damage and repair in uroepithelial cells(2023/12/22)
作者：Xu Zhang, Lifang Liu, Jun Wang
期刊：ENVIRONMENT INTERNATIONAL
DOI：10.1016/j.envint.2023.108407
影响因子 ：11.800
引用产品：CL-0222
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WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity(2023/01/07)
作者：Xiaosong Wei, Beibei Wang, Zixin Wu
期刊：CANCER LETTERS
DOI：10.1016/j.canlet.2023.216058
影响因子 ：9.700
引用产品：CL-0002 CL-0125 CL-0222 CL-0227 CL-0463 CL-0628 PM150410 PM150710 PM150910 PM151010
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A modified biodegradable mesh ureteral stent for treating ureteral stricture disease(2022/11/17)
作者：Yichun Wang, Xiaohan Ren, Chengjian Ji, Da Zhong, Xiyi Wei, Zheng Zhu, Xuan Zhou, Xi Zhang, Shuai Wang, Chao Qin, Ninghong Song
期刊：Acta Biomaterialia
DOI：10.1016/j.actbio.2022.11.022
影响因子 ：9.300
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RETRACTED: Baicalein inhibits proliferation and migration of bladder cancer cell line T24 by down-regulation of microRNA-106(2018/11/01)
作者：Liangzhen Jiang, Haibin Song, Hongbo Guo
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2018.08.107
影响因子 ：7.500
引用产品：CL-0222
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Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis(2022/11/29)
作者：Qi Li, Yifan Hong, Jing Chen, Xiazhu Zhou, Xiaomao Tian, Yihang Yu, Lianju Shen, Chunlan Long, Miao Cai, Shengde Wu, Guanghui Wei
期刊：Cells
影响因子 ：6.000
引用产品：CL-0222
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circCD2AP promotes epithelial mesenchymal transition and stemness in bladder cancer by regulating FOXQ1/USP21 axis(2023/11/14)
作者：Jinrong Wang, Jing Tan, Yichuan Zhang
期刊：iScience
DOI：10.1016/j.isci.2023.108447
影响因子 ：5.800
引用产品：CL-0222
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A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration(2021/08/06)
作者：Jiaochen Luan, Tengyue Zeng, Qijie Zhang
期刊：Cancer Cell International
DOI：10.1186/s12935-021-02096-3
影响因子 ：5.800
引用产品：CL-0222
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Identification of immuno-infiltrating MAP1A as a prognosis-related biomarker for bladder cancer and its ceRNA network construction(2022/11/02)
作者：Xiaoyue Lyu, Yujie Qiang, Bo Zhang
期刊：Frontiers in Oncology
影响因子 ：5.738
引用产品：CL-0222
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circ_100984‐miR‐432‐3p axis regulated c‐Jun/YBX‐1/β‐catenin feedback loop promotes bladder cancer progression(2021/02/10)
作者：Liang Tong, Huihui Yang, Wei Xiong
期刊：Cancer Science
影响因子 ：5.700
引用产品：CL-0222
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Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.(2022/09/21)
作者：Longfei Yang, Yuwei Zhang, Yang Wang
期刊：Frontiers in Pharmacology
影响因子 ：5.600
引用产品：CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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Inhibition of the NF-κB Signaling Pathway Alleviates Pyroptosis in Bladder Epithelial Cells and Neurogenic Bladder Fibrosis(2023/07/06)
作者：Jing Chen, Qi Li, Yifan Hong
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0222
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Immunogenic Cell Death Associated Molecular Patterns and the Dual Role of IL17RA in Interstitial Cystitis/Bladder Pain Syndrome(2023/02/23)
作者：Wei Zhang, Xiaodong Liu, Jiawen Wang
期刊：Biomolecules
影响因子 ：5.500
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Unveiling clinical significance and tumor immune landscape of CXCL12 in bladder cancer: Insights from multiple omics analysis(2023/12/12)
作者：Zhouting Tuo, Dechao Feng, Zhiwei Jiang
期刊：Chinese Journal of Cancer Research
DOI：10.21147/j.issn.1000-9604.2023.06.12
影响因子 ：5.100
引用产品：CL-0222
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Preparation and characterization of PLGA nano-drug delivery system co-loaded with tranilast/gallium phytate for stent coating(2024/05/23)
作者：Kaichao Wen, Zhengan Li, Jiheng Liu
期刊：JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI：10.1016/j.jddst.2024.105812
影响因子 ：5.000
引用产品：CL-0222
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CRTAC1 (Cartilage acidic protein 1) inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process in bladder cancer by downregulating Yin Yang 1 (YY1) to inactivate the TGF-β pathway(2021/11/24)
作者：Jianghua Yang, Li Fan, Xiaoxing Liao
期刊：Bioengineered
DOI：10.1080/21655979.2021.1974645
影响因子 ：4.900
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Transcriptomic profiling and risk assessment in bladder cancer: Insights from copper death-related genes(2024/05/27)
作者：Xu Wang, Long Jin, Xiaoyu Zhang
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111237
影响因子 ：4.800
引用产品：CL-0222
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POLR3G promotes EMT via PI3K/AKT signaling pathway in bladder cancer(2023/11/07)
作者：Hualin Chen, Lin Ma, Wenjie Yang
期刊：FASEB JOURNAL
影响因子 ：4.800
引用产品：CL-0222
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The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis(2022/11/21)
作者：Jiani He, Changming Dong, Hao Zhang, Yuanjun Jiang, Tao Liu, Xiaojun Man
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2022.110527
影响因子 ：4.800
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A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance(2023/04/08)
作者：Longfei Yang, Yuwei Zhang, Yifan Tang
期刊：Scientific Reports
DOI：10.1038/s41598-023-27975-9
影响因子 ：4.600
引用产品：CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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A novel anoikis-related gene signature identifies LYPD1 as a novel therapy target for bladder cancer(2024/02/08)
作者：Zhen Song, Shikai Gui, Shuaiyun Xiao
期刊：Scientific Reports
DOI：10.1038/s41598-024-53272-0
影响因子 ：4.600
引用产品：CL-0222
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Identification and preliminary analysis of hub genes associated with bladder cancer progression by comprehensive bioinformatics analysis(2024/02/02)
作者：Han Wang, Junjie Liu, Yanyan Lou
期刊：Scientific Reports
DOI：10.1038/s41598-024-53265-z
影响因子 ：4.600
引用产品：CL-0222
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NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway( 2022/01/02)
作者：Bo Li, Qian Xiao, Liping Shan
期刊：Cell Cycle
DOI：10.1080/15384101.2021.2021050
影响因子 ：4.300
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BHLHE41 inhibits bladder cancer progression via regulation of PYCR1 stability and thus inactivating PI3K/AKT signaling pathway(2024/05/29)
作者：Shuai Xiao, Junjie Chen, Yongbao Wei
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-024-01889-2
影响因子 ：4.200
引用产品：CL-0222
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CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis(2024/01/01)
作者：Peng Zhang, Qian Yang, Xulong Chen
期刊：Journal of Cancer
影响因子 ：3.900
引用产品：CL-0222
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circCEP128 Knockdown Suppresses Bladder Cancer Progression via Regulating microRNA-515-5p/SDC1 Axis(2022/12/21)
作者：Guanghui Cao, Chan Zhang, Xiangyong Tian
期刊：Cancer Management and Research
影响因子 ：3.602
引用产品：CL-0222
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HEATR3 involved in the cell proliferation, metastasis and cell cycle development of bladder cancer acts as a tumor suppressor(2023/07/31)
作者：Xia Dou, Xiaoya Ma, Wenting Meng
期刊：MOLECULAR GENETICS AND GENOMICS
DOI：10.1007/s00438-023-02046-w
影响因子 ：3.100
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PC4 promotes bladder cancer progression and stemness by directly interacting with Sp1 to transcriptionally activate the Wnt5a/β-catenin pathway(2024/05/26)
作者：Benhuang Yan, Peng Luo, Heping Qiu
期刊：PATHOLOGY RESEARCH AND PRACTICE
影响因子 ：2.800
引用产品：CL-0222
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The mechanism of PFK-1 in the occurrence and development of bladder cancer by regulating ZEB1 lactylation(2024/03/13)
作者：Rong Wang, Fei Xu, Zhengjia Yang
期刊：BMC Urology
DOI：10.1186/s12894-024-01444-5
影响因子 ：2.000
引用产品：CL-0222
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Hsa_circ_0008035 Knockdown Inhibits Bladder Cancer Progression through miR-1184/RAP2B Axis(2023/03/23)
作者：Yang Fu, Kun Liu, Xi Jiang
期刊：UROLOGIA INTERNATIONALIS
影响因子 ：1.600
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