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![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-1.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-2.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-3.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-4.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-5.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-6.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/product/cell-line-new.jpg)
产品概述
| 名称 | LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确) |
| 别称 | LL/2 (LLc1); LL/2(LLc1); LL/2; LL2; LLC1; LLC; Lewis lung carcinoma line 1; Lewis lung carcinoma; Lewis-Lung; Lewis Lung |
| 种属 | 小鼠 |
| 生长特性 | 半贴半悬 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | LLC细胞是小鼠Lewis肺癌细胞。 |
| 年龄（性别） | 不详 |
| 组织来源 | 肺 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肺癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, in C57BL mice. |
| 抗原表达情况 | H-2b |
| 保藏机构 | ATCC; CRL-1642 BCRC; 60050 BCRJ; 0145 ECACC; 90020104 |
STR鉴定
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STR位点信息
18-3 15,16 6-7 15 5-5 16,17 X-1 25,26 1-2 18,19 7-1 27.2 8-1 16,17 1-1 15,16,17,18 19-2 13 15-3 24.3,25.3,26.3 12-1 17 6-4 18 4-2 21.3,23.3 3-2 13,14 2-1 16 13-1 18.1
11-2 13.3,14.3,15.3 17-2 14,15 -
STR鉴定图
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参考文献
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Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy(2023/09/11)
作者：Zhiguo Fang, Chenlei Wang, Jingrun Yang
期刊：Nature Nanotechnology
DOI：10.1038/s41565-023-01501-4
影响因子 ：38.300
引用产品：CL-0140
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A method for predicting drugs that can boost the efficacy of immune checkpoint blockade(2024/03/18)
作者：Yun Xia, Xin Li, Nana Bie
期刊：NATURE IMMUNOLOGY
DOI：10.1038/s41590-024-01789-x
影响因子 ：30.500
引用产品：CL-0140
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Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation(2023/07/26)
作者：Jiaqi Meng, Yanlin Lv, Weier Bao
期刊：Nature Communications
DOI：10.1038/s41467-023-40207-y
影响因子 ：16.600
-
Cholesterol removal improves performance of a model biomimetic system to co-deliver a photothermal agent and a STING agonist for cancer immunotherapy(2023/08/22)
作者：Lin Li, Mengxing Zhang, Jing Li
期刊：Nature Communications
DOI：10.1038/s41467-023-40814-9
影响因子 ：16.600
-
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment(2024/02/08)
作者：Yin Li, Manling Jiang, Ling Aye
期刊：Nature Communications
DOI：10.1038/s41467-024-45340-w
影响因子 ：16.600
引用产品：CL-0140
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Brain Metastasis from EGFR-Mutated Non-Small Cell Lung Cancer: Secretion of IL11 from Astrocytes Up-Regulates PDL1 and Promotes Immune Escape(2024/05/02)
作者：Mengyi Tang, Mingxin Xu, Jian Wang
期刊：Advanced Science
影响因子 ：15.100
引用产品：CL-0140
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Autologous-cancer-cryoablation-mediated nanovaccine augments systematic immunotherapy(2023/02/21)
作者：Zhongyang Yu, Dawei Wang, Yuxia Qi
期刊：Materials Horizons
影响因子 ：13.300
引用产品：CL-0140
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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner(2023/02/03)
作者：Yiru Long, Runqiu Chen, Xiaolu Yu
期刊：Cancer Immunology Research
DOI：10.1158/2326-6066.CIR-22-0439
影响因子 ：10.100
引用产品：CL-0005 CL-0007 CL-0019 CL-0071 CL-0105 CL-0129 CL-0140 CL-0196 CL-0246 CL-0319
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Nerve Growth Factor/Tyrosine Kinase A Receptor Pathway Enhances Analgesia in an Experimental Mouse Model of Bone Cancer Pain by Increasing Membrane Levels of δ-Opioid Receptors(2024/03/08)
作者：Bufan Kan, Xingyun Liu, Mingming Han
期刊：ANESTHESIOLOGY
DOI：10.1097/ALN.0000000000004880
影响因子 ：8.800
引用产品：CL-0140
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Metal-Phenolic network pH-Sensitive Nanoparticle-Enabled Chemo/Chemodynamic therapy for lung cancer(2023/06/08)
作者：Daiwang Shi, Siyi Li, Wenhan Liu
期刊：MATERIALS & DESIGN
DOI：10.1016/j.matdes.2023.112072
影响因子 ：8.400
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Luteolin Relieves Lung Cancer-Induced Bone Pain by Inhibiting NLRP3 Inflammasomes and Glial Activation in the Spinal Dorsal Horn in Mice( 2021/12/25)
作者：Yongsheng Zhou, Yue Cui, Jiaxin Zheng
期刊：Phytomedicine
DOI：10.1016/j.phymed.2021.153910
影响因子 ：7.900
引用产品：CL-0140
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Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis(2023/09/22)
作者：Junsong Ren, Wen Bai, Jingjuan Ding
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04503-x
影响因子 ：7.400
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Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo(2021/03/17)
作者：Huiqiong Zhang, Xiaofang Xie, Gangmin Li
期刊：Phytotherapy Research
DOI：10.1002/ptr.7154
影响因子 ：7.200
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Intelligent triggering of nanomicelles based on a ROS-activated anticancer prodrug and photodynamic therapy (PDT)-synergistic therapy for lung cancers(2022/08/03)
作者：Lixue Chen, Ruping Xu, Yanfang Ding
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2022.114622
影响因子 ：6.700
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Radiation-induced bystander effect on the genome of bone marrow mesenchymal stem cells in lung cancer(2022/10/14)
作者：Yiming Zhang, Liying Zhang, Yangyang Li
期刊：ANTIOXIDANTS & REDOX SIGNALING
影响因子 ：6.600
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DHA/EPA-Enriched Phosphatidylcholine Suppresses Tumor Growth and Metastasis via Activating Peroxisome Proliferator-Activated Receptor γ in Lewis Lung Cancer Mice(2021/01/06)
作者：Yuanyuan Liu, Yingying Tian, Weizhen Cai
期刊：Journal Of Agricultural And Food Chemistry
影响因子 ：6.100
引用产品：CL-0140
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Reassembling of albumin-bound paclitaxel mitigates myelosuppression and improves its antitumoral efficacy via neutrophil-mediated targeting drug delivery(2022/02/21)
作者：Yuxin Chen, Lulu Han, Xiaoyan Qiu
期刊：Drug Delivery
DOI：10.1080/10717544.2022.2046892
影响因子 ：6.000
引用产品：CL-0140
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Dynamic Changes of the Gut Microbiota and Its Functional Metagenomic Potential during the Development of Non-Small Cell Lung Cancer(2024/03/28)
作者：Cuijiao Feng, Na Li, Guangqi Gao
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0140
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Bifunctional molecular probe targeting tumor PD-L1 enhances anti-tumor efficacy by promoting ferroptosis in lung cancer mouse model(2024/03/04)
作者：Chenxu Shao, Xiaoping Yan, Shangjie Pang
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.111781
影响因子 ：5.600
引用产品：CL-0140
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Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer(2022/02/25)
作者：Qianqian Zhang, Jianwei Bao, Tijie Duan
期刊：Pharmaceutics
DOI：10.3390/pharmaceutics14030510
影响因子 ：5.400
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Shashen-Maidong Decoction inhibited cancer growth under intermittent hypoxia conditions by suppressing oxidative stress and inflammation(2022/09/02)
作者：Yuying Zheng, Shengchang Yang, Jianchao Si
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0140
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Jolkinolide B inhibits proliferation or migration and promotes apoptosis of MCF-7 or BT-474 breast cancer cells by downregulating the PI3K-Akt pathway(2021/08/28)
作者：Yang Wang, Shiyang Shen, Lei Liu
期刊：Journal Of Ethnopharmacology
影响因子 ：5.400
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E74‑like ETS transcription factor 5 facilitates cell proliferation through regulating the expression of adenomatous polyposis coli 2 in non‑small cell lung cancer(2023/07/11)
作者：Jing Wen, Genggeng Qin, Zhaojing Jiang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
影响因子 ：5.400
引用产品：CL-0140
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Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway(2022/09/17)
作者：Chengwei Yang, Fang Kang, Xiang Huang
期刊：NEUROPHARMACOLOGY
DOI：10.1016/j.neuropharm.2022.109254
影响因子 ：5.300
引用产品：CL-0140
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A novel selenium nanocomposite modified by AANL inhibits tumor growth by upregulating CLK2 in lung cancer(2024/05/15)
作者：Yueyang Zhang, Ying Chen, Bo Wang
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2024.107459
影响因子 ：5.100
引用产品：CL-0140
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Black phosphorus nanoparticles for dual therapy of non-small cell lung cancer(2022/02/02)
作者：Zhongxiao Lin, Qiudi Deng, Qi Fang
期刊：Journal Of Drug Targeting
DOI：10.1080/1061186X.2022.2032093
影响因子 ：5.016
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Alterations of lung microbiota in patients with non-small cell lung cancer(2022/03/07)
作者：Wen Zeng, ChengZhu Zhao, Mengge Yu
期刊：Bioengineered
DOI：10.1080/21655979.2022.2045843
影响因子 ：4.900
引用产品：CL-0140
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Combinational delivery of TLR4 and TLR7/8 agonist enhanced the therapeutic efficacy of immune checkpoint inhibitors to colon tumor(2024/03/20)
作者：Mengjiao Wang, Quan Wan, Chenglv Wang
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-024-04966-6
影响因子 ：4.300
引用产品：CL-0140
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Study the inhibitory effect and mechanism of the ethanol extract of deziyangxin on LLC cells(2023/07/27)
作者：Yun Yi, Yahui Jiang, Bobo Bai
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e18712
影响因子 ：4.000
引用产品：CL-0140
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Transplantation of feces from mice with Alzheimers disease promoted lung cancer growth(2022/01/24)
作者：Wangyu Bi, Shanglin Cai, Zhongci Hang
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2022.01.078
影响因子 ：3.100
引用产品：CL-0140
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Gut microbiome affects the response to immunotherapy in non-small cell lung cancer(2024/04/04)
作者：Shengnan Ren, Lingxin Feng, Haoran Liu
期刊：Thoracic Cancer
影响因子 ：2.900
引用产品：CL-0140
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Depression promotes lung carcinoma progression by regulating the tumor microenvironment in tumor-bearing models of C57BL/6J mice(2021/5/29)
作者：Sainan Cui, Huiyuan Lin, Yongfei Cui
期刊：Neuroscience Letters
DOI：10.1016/j.neulet.2021.135851
影响因子 ：2.500
引用产品：CL-0140
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Sambucus adnata Polysaccharide SPS-1 Inhibits Growth of Transplanted Lung Cancer via Polarizing Tumor Associated Macrophage From M2 into M1(2023/07/10)
作者：Lei Yuan, Yadong Hu
期刊：Natural Product Communications
影响因子 ：1.800
引用产品：CL-0140
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