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产品概述
名称 | NCI-H1975 (人肺腺癌细胞) (STR鉴定正确) |
别称 | H1975; H-1975 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | NCI-H1975细胞是于1988年7月从一名女性(无抽烟史)非小细胞肺腺癌组织中分离得到的。 |
年龄(性别) | 女性 |
组织来源 | 器官:肺;疾病:腺癌;非小细胞肺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~28-45 hours |
保藏机构 | ATCC; CRL-5908 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 17 D3S1358 14,15 D5S818 11,12 D7S820 8,11 D8S1179 13,16 D13S317 10,13 D16S539 9,12 D18S51 13 D19S433 15,15.2 D21S11 28 FGA 21,24 PentaD 12,13 PentaE 12,16 TH01 7 TPOX 8,11 vWA 18 D6S1043 12 D12S391 17 D2S441 10,11 -
STR鉴定图
参考文献
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High-throughput and proteome-wide discovery of endogenous biomolecular condensates(2024/03/18)
作者:Pengjie Li, Peng Chen, Fukang Qi
期刊:Nature Chemistry
DOI:10.1038/s41557-024-01485-1
影响因子 :21.800
引用产品:CL-0298
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Highly Multiplexed, Efficient, and Automated Single-Cell MicroRNA Sequencing with Digital Microfluidics.(2023/11/28)
作者:Yingwen Chen, Xuanqun Wang, Xing Na
期刊:Small Methods
影响因子 :12.400
引用产品:CL-0298
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Multivalent DNA Flowers for High-Performance Isolation, Detection, and Release of Tumor-Derived Extracellular Vesicles(2023/11/26)
作者:Yongan Ren, Ke Ge, Wei Lu
期刊:ACS Applied Materials & Interfaces
影响因子 :9.500
引用产品:CL-0298
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Thioredoxin reductase 1 inhibitor shikonin promotes cell necroptosis via SecTRAPs generation and oxygen-coupled redox cycling(2021/12/30)
作者:Yue Zhang, Shibo Sun, Weiping Xu
期刊:Free Radical Biology And Medicine
DOI:10.1016/j.freeradbiomed.2021.12.314
影响因子 :8.101
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Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis(2024/03/23)
作者:Yuanyuan Zeng, Jian Zhao, Zhengyan Wu
期刊:npj Precision Oncology
DOI:10.1038/s41698-024-00574-1
影响因子 :7.900
引用产品:CL-0298
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LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer(2017/01/12)
作者:Zhihong Zhao, Ju Wang, Shengfa Wang
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2016.12.122
影响因子 :7.500
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Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells(2021/12/23)
作者:Shibo Sun, Yue Zhang, Weiping Xu
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.112546
影响因子 :7.419
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Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5(2023/09/26)
作者:Pengming Pan, Tongtong Geng, Zhongtang Li
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.3c00864
影响因子 :7.300
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Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo(2021/03/17)
作者:Huiqiong Zhang, Xiaofang Xie, Gangmin Li
期刊:Phytotherapy Research
DOI:10.1002/ptr.7154
影响因子 :7.200
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Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer(2022/11/27)
作者:Tan, Bo, Zhang, Jingwei, Wang, Wen, Ma, Haibo, Yang, Yuanyuan
期刊:APOPTOSIS
DOI:10.1007/s10495-022-01789-y
影响因子 :7.200
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Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines(2016/01/26)
作者:Haiqing Yu, Yanxia Li, Yang Ge
期刊:European Journal of Medicinal Chemistry
DOI:DOI: 10.1016/j.ejmech.2016.01.045
影响因子 :6.700
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Activation of Hypoxia Inducible Factor-1 Alpha-Mediated DNA Methylation Enzymes (DNMT3a and TET2) Under Hypoxic Conditions Regulates S100A6 Transcription to Promote Lung Cancer Cell Growth and Metastasis(2024/03/18)
作者:Tengfei Wang, Genbao Zhu, Bo Wang
期刊:ANTIOXIDANTS & REDOX SIGNALING
影响因子 :6.600
引用产品:CL-0298
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Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology(2023/11/27)
作者:Mawusse K.I. Attiogbe, Hongyi Zhao
期刊:LIFE SCIENCES
影响因子 :6.100
引用产品:CL-0298
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LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes(2023/09/05)
作者:Liyao Dong, Lin Zhang, Xinyun Zhao
期刊:Cancer Cell International
DOI:10.1186/s12935-023-03036-z
影响因子 :5.800
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Long noncoding RNA FBXL19‐AS1 induces tumor growth and metastasis by sponging miR‐203a‐3p in lung adenocarcinoma(2019/09/20)
作者:Liming Wang, Xin Zhang, Yang Liu
期刊:Journal of Cellular Physiology
影响因子 :5.600
引用产品:CL-0298
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C1GALT1, Negatively Regulated by miR-181d-5p, Promotes Tumor Progression via Upregulating RAC1 in Lung Adenocarcinoma(2021/070/7)
作者:Xiaoxia Dong, Yongyu Liu, Xinzhou Deng
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Prognostic Value of Genomic Instability of m 6 A-Related lncRNAs in Lung Adenocarcinoma(2022/03/03)
作者:Rui Li, JianPing Li, TingTing Liu
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Inhibition effect of oxyepiberberine isolated from Coptis chinensis franch. On non-small cell lung cancer based on a network pharmacology approach and experimental validation(2021/6/1)
作者:Ying Zhang, Yunfeng Yao, Yingjie Fu
期刊:Journal Of Ethnopharmacology
影响因子 :5.400
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Structurally Diverse Diterpenes from the South China Sea Soft Coral Sarcophyton trocheliophorum(2023/01/20)
作者:Yuting Song, Dandan Yu, Mingzhi Su
期刊:Marine Drugs
影响因子 :5.400
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SLCO4A1, as a novel prognostic biomarker of non‑small cell lung cancer, promotes cell proliferation and migration(2024/01/23)
作者:Shihao Li, Zihao Li, Lan Huang
期刊:INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 :5.200
引用产品:CL-0298
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Exosomal Delivery of FTO Confers Gefitinib Resistance to Recipient Cells through ABCC10 Regulation in an m6A-dependent Manner(2021/02/09)
作者:Peng Xiao, Yukang Liu, Wei Han
期刊:Molecular Cancer Research
DOI:10.1158/1541-7786.MCR-20-0541
影响因子 :5.200
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Guided Isolation of An Uncommon Cembranoid Orthoester, Sarcotortin A, and Three Skeletal Diverse Terpenoids from the Hainan Soft Coral Sarcophyton tortuosum Based on Molecular Networking Strategy(2022/12/23)
作者:Zihui Chen, Dandan Yu, Cong Li
期刊:CHEMISTRY-A EUROPEAN JOURNAL
影响因子 :5.020
引用产品:CL-0298
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lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma(2023/12/01)
作者:Zhuo Ting, Zuotao Wu, Chuyi Yang
期刊:Non-coding RNA Research
DOI:10.1016/j.ncrna.2023.11.013
影响因子 :5.000
引用产品:CL-0298
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GPR37-centered ceRNA network contributes to metastatic potential in lung adenocarcinoma: Evidence from high-throughput sequencing(2023/11/16)
作者:Chuanhui Chen, Mengzhi Wan, Xiong Peng
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101819
影响因子 :5.000
引用产品:CL-0298
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Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression(2022/02/14)
作者:Hongyu Huang, Chuyi Yang, Qichen Zhang
期刊:Bioengineered
DOI:10.1080/21655979.2022.2037871
影响因子 :4.900
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GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway(2023/04/19)
作者:Zhitao Chen, Yanhui Song, Peipei Li
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110685
影响因子 :4.800
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Comprehensive analysis of cuproptosis and copper homeostasis genotyping and related immune land scape in lung adenocarcinoma(2023/10/02)
作者:Dayuan Luo, Xiang Wang, Wei Feng
期刊:Scientific Reports
DOI:10.1038/s41598-023-43795-3
影响因子 :4.600
引用产品:CL-0298
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IMP4 Silencing Inhibits the Malignancy of Lung Adenocarcinoma via ERK Pathway(2022/10/22)
作者:Ruzhen Li, Zhaohui Han, Wei Ma
期刊:Journal of Oncology
影响因子 :4.501
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DNA repair/recombination protein 54L promotes the progression of lung adenocarcinoma by activating mTORC1 pathway(2022/12/01)
作者:Changjiang Liu, Wei Ren, Zhixin Zhang
期刊:Human Cell
DOI:10.1007/s13577-022-00832-z
影响因子 :4.374
引用产品:CL-0298
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LncRNA surfactant associated 1 activates large tumor suppressor kinase 1/Yes-associated protein pathway via modulating hypoxic exosome-delivered miR-4766–5p to inhibit lung adenocarcinoma metastasis(2022/10/22)
作者:Weiqiang Zhang, Miaochun Bai, Keqiang Liu
期刊:INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI:10.1016/j.biocel.2022.106317
影响因子 :4.000
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Integrated analysis of purine metabolism assists in predicting prognosis and treatment decisions for patients with lung adenocarcinoma(2024/04/04)
作者:Tingting Zhang, Ruhua Chen, Xiangyu Su
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e29290
影响因子 :4.000
引用产品:CL-0298
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SLC7A5 is a lung adenocarcinoma-specific prognostic biomarker and participates in forming immunosuppressive tumor microenvironment(2022/10/02)
作者:Yong Liu, Guoyuan Ma, Jichang Liu
期刊:Heliyon
DOI:10.1016/j.heliyon.2022.e10866
影响因子 :4.000
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Identification of ALG3 as a potential prognostic biomarker in lung adenocarcinoma(2023/07/08)
作者:Yinjiao Yuan, BaoCheng Xie, Dongbo Guo
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e18065
影响因子 :4.000
引用产品:CL-0298
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Comprehensive Analysis of a Novel Immune-Related Gene Signature in Lung Adenocarcinoma(2022/10/19)
作者:Hongxiang Feng, Chaoyang Liang, Yuhui Shi
期刊:Journal of Clinical Medicine
影响因子 :3.900
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Lactate dehydrogenase D serves as a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma(2023/08/16)
作者:Yu Zhang, Tianyi Zhang, Yingdong Zhao
期刊:BMC CANCER
DOI:10.1186/s12885-023-11221-6
影响因子 :3.800
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TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT(2021/11/7)
作者:Danjie Zhang, Liangzhang Sun, Jin Zhang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2021.115793
影响因子 :3.800
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RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression(2021/07/28)
作者:Min Wu, Mengmeng Jin, Xiaohui Cao
期刊:Drug Development Research
影响因子 :3.800
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Comprehensive analysis of an immune infiltrate-related competitive endogenous RNA network reveals potential prognostic biomarkers for non-small cell lung cancer(2021/12/02)
作者:Caizhi Yang, Leihao Hu, Zhongyu Huang
期刊:PLoS One
DOI:10.1371/journal.pone.0260720
影响因子 :3.700
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SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway(2020/10/27)
作者:Yan Feng, Xiangyu Guo, Huaping Tang
期刊:Annals of Translational Medicine
影响因子 :3.616
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Multi-omics analysis of expression profile and prognostic values of connexin family in LUAD(2023/07/17)
作者:Peng Jiang, Xingfa Huo, Bowen Dong
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-023-05075-5
影响因子 :3.600
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Circ_0006324 regulates cell proliferation, cell-cycle progression, apoptosis, and glycolysis of non-small cell lung cancer cells through miR-496/TRIM59 axis(2023/08/07)
作者:Tao Wang, Xu Zhu, Kai Wang
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.600
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Silencing of circ_0088036 inhibits growth and invasion of lung adenocarcinoma through miR-203/SP1 axis(2024/03/27)
作者:Xiuhua Liu, Yan Feng, Linna Wang
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.600
引用产品:CL-0298
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Intelligent Genetic Decoding System Based on Nucleic Acid Isothermal Amplification for Non-Small Cell Lung Cancer Diagnosis(2023/03/12)
作者:Xiaonan Liu, Jiaxing Zhang, Kai Hua
期刊:Micromachines
影响因子 :3.400
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Hydrogen Peroxide-Inducible PROTACs for Targeted Protein Degradation in Cancer Cells(2023/07/18)
作者:Dehao Yu, Heli Fan, Zhili Zhou
期刊:CHEMBIOCHEM
影响因子 :3.200
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IGF2BP1 enhances the stability of SIK2 mRNA through m6A modification to promote non-small cell lung cancer progression(2023/10/12)
作者:Yan Xu, Li Xu, Yi Kong
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.10.045
影响因子 :3.100
引用产品:CL-0298
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Mechanisms analysis for Formononetin counteracted-Osimertinib resistance in non-small cell lung cancer cells: From the insight into the gene transcriptional level(2023/12/28)
作者:Runyang Yin, Jing Gao, Yang Liu
期刊:Chemical Biology & Drug Design
影响因子 :3.000
引用产品:CL-0298
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Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma(2023/02/24)
作者:Rui Chen, Zhiping Wang, Tianzhu Lu
期刊:Thoracic Cancer
影响因子 :2.900
引用产品:CL-0016 CL-0161 CL-0165 CL-0166 CL-0298 CL-0668 CM-0161
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Mechanism of Key Ingredient of Astragalus membranaceus on Lung Adenocarcinoma via PI3K/AKT Signaling Clarified by Utilizing Network Pharmacology Approach and Experimental Validation(2022/08/31)
作者:Yuanchun Wang, Jianrong Hui, Gang Xiao
期刊:Chinese Journal of Integrative Medicine
影响因子 :2.900
引用产品:CL-0298
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MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34(2023/06/13)
作者:Junhua Wu, Chongmei Yue, Weiguo Xu
期刊:Oncology Letters
影响因子 :2.900
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Calponin 3 suppresses proliferation, migration and invasion of non‑small cell lung cancer cells(2021/7/1)
作者:Chenglin Yang, Shiping Zhu, Weifeng Feng
期刊:Oncology Letters
影响因子 :2.900
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Anti-tumor cembrane diterpenoids from the South China Sea soft coral Lobophytum sp.(2023/02/28)
作者:Fan Yang, Yuting Song, Dandan Yu
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
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Long noncoding RNA LINC00968 inhibits proliferation, migration and invasion of lung adenocarcinoma through targeting miR-22-5p/CDC14A axis(2021/09/14)
作者:Chao Wu, Xuzhao Bian, Liyuan Zhang
期刊:3 BIOTECH
DOI:10.1007/s13205-021-02981-8
影响因子 :2.893
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Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p(2020/01/10)
作者:Runa Dao, Muli Wudu, Linping Hui
期刊:Pathology Research and Practice
影响因子 :2.800
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LncRNA PCAT6 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of lung adenocarcinoma cell by targeting miR-545-3p(2023/02/14)
作者:Chuyi Yang, Hongyu Huang, Yongpeng Li
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08259-x
影响因子 :2.800
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Anticancer roles of let‑7f‑1‑3p in non‑small cell lung cancer via direct targeting of integrin β1(2021/9/16)
作者:Yanan Yang, Yuanrong Liu,Ning Xie
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
引用产品:CL-0298
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Dysregulated expression of microRNA involved in resistance to osimertinib in EGFR mutant non-small cell lung cancer cells(2023/04/24)
作者:Dianbao Zhang, Yukun Yang, Yixin Kang
期刊:Journal of Thoracic Disease
影响因子 :2.500
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CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis(2023/12/21)
作者:Xuan Zhao, Xiaojing Xing, Yongkai Wu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-023-10611-6
影响因子 :2.400
引用产品:CL-0298
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Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者:Wenjing Lu, Zhigao Yu, Jun Liu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10312-6
影响因子 :2.400
引用产品:164210-50 CL-0016 CL-0094 CL-0298 CM-0016 CM-0094 CM-0298 PB180120 PM150110 PM150210 PM150910
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Hsa_circ_0080608 Attenuates Lung Cancer Progression by Functioning as a Competitive Endogenous RNA to Regulate the miR-661/ADRA1A Pathway(2023/10/11)
作者:Chengbo Ren, Ling Cui, Ruibiao Li
期刊:HORMONE AND METABOLIC RESEARCH
影响因子 :2.200
引用产品:CL-0298
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PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway(2024/01/19)
作者:Junqi Lv, Shengmao Ma, Xiaowen Wang
期刊:Genes & Genomics
DOI:10.1007/s13258-023-01484-5
影响因子 :2.100
引用产品:CL-0298
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USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway(2022/12/08)
作者:Yuhui Zhou, Yunxia Zhao, Wei Ma
期刊:Discover Oncology
DOI:10.1007/s12672-022-00600-3
影响因子 :0.000
引用产品:CL-0298
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