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产品概述
IMDM（Iscove’s Modified Dulbecco Medium）即Iscove改良的DMEM培养基，是Guilber 和Iscove在1976年设计的，用以培养红细胞前体细胞和巨噬细胞。IMDM培养基在DMEM培养基的基础上添加了硒、HEPES、丙酮酸钠以及额外的氨基酸和维生素，营养非常丰富，非常适合于快速增殖，高密度细胞培养。IMDM培养基不仅可以培养有特殊营养要求的细胞（如小鼠B淋巴细胞，LPS刺激的B细胞，骨髓造血细胞，T淋巴细胞以及各种杂交瘤细胞），还可以作为一些独特的无血清培养基的基础液。
本产品含有多类细胞培养所需的氨基酸、维生素、无机盐等多种成分，但不含蛋白质、脂类或任何生长因子，故此产品需搭配血清或无血清添加物使用。
成分说明
形态 | 液体 |
浓度 | 1× |
规格 | 500mL |
pH | 7.2-7.4 |
L-谷氨酰胺 | 4 mM |
NaHCO3 | 3024 mg/L |
D-葡萄糖 | 4500 mg/L |
丙酮酸钠 | 1 mM |
HEPES缓冲剂 | 25 mM |
酚红指示剂 | 15 mg/L |
储存条件 | 2 -8℃，避光 |
运输条件 | 常温 |
有效期 | 18个月 |
注意事项
1、本产品经0.1 μm过滤除菌，使用时应注意无菌操作，避免污染；
2、为保持本产品的最佳使用效果，请勿进行冻融处理；
3、本产品仅用于科研或进一步研究使用，不用于诊断和治疗。
参考文献
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A Divalent Chikungunya and Zika Nanovaccine with Thermostable Self-assembly Multivalent Scaffold LS-SUMO(2024/02/10)
作者：Qianlin Li, Jinsong Zhang, Qiang Deng
期刊：Advanced Healthcare Materials
影响因子 ：10.000
引用产品：PM150510
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Megakaryocytes participate in the occurrence of bleomycin-induced pulmonary fibrosis(2019/09/09)
作者：Yan Zhou, Bo Zhang, Chen Li
期刊：Cell Death & Disease
影响因子 ：9.000
引用产品：PM150510
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LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit(2021/05/18)
作者：Yanling Tao, Jingjing Zhang, Lulu Chen
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-03767-9
影响因子 ：9.000
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DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation(2021/09/21)
作者：Tanjing Song, Qingli Zou, Yingying Yan
期刊：Cell Reports
DOI：10.1016/j.celrep.2021.109739
影响因子 ：8.800
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Using Surface Immunogenic Protein as a Carrier Protein to Elicit Protective Antibody to Multiple Serotypes for Candidate Group B Streptococcal Glycan Conjugate Vaccines(2024/05/24)
作者：Huiqi Duan, Wenhua Huang, Qingyu Lv
期刊：Vaccines
影响因子 ：7.800
引用产品：PM150510
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Activation of ryanodine-sensitive calcium store drives pseudo-allergic dermatitis via Mas-related G protein-coupled receptor X2 in mast cells(2023/06/19)
作者：Zhao Wang, Xi Zhao, Hongmei Zhou
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1207249
影响因子 ：7.300
引用产品：PM150510
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PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression(2023/04/10)
作者：Jia Ma, Wenyang Zhou, Yifeng Yuan
期刊：Cancer Gene Therapy
DOI：10.1038/s41417-023-00609-y
影响因子 ：6.400
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Anti‑silencing function 1B promotes the progression of pancreatic cancer by activating c‑Myc(2022/11/17)
作者：Min Zhang, Luyang Zhang, Minghe Zhou
期刊：INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 ：5.884
引用产品：PM150510
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Itraconazole inhibits tumor growth via CEBPB-mediated glycolysis in colorectal cancer(2024/01/26)
作者：Yong Zhang, Lu Li, Feifei Chu
期刊：CANCER SCIENCE
影响因子 ：5.700
引用产品：PM150510
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GID2 interacts with CDKN3 and regulates pancreatic cancer growth and apoptosis(2023/02/23)
作者：Xin Deng, Jia Ma, Wenyang Zhou
期刊：LABORATORY INVESTIGATION
DOI：10.1016/j.labinv.2023.100122
影响因子 ：5.000
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Aberrant expression of PELI1 caused by Jagged1 accelerates the malignant phenotype of pancreatic cancer(2023/08/30)
作者：Wenyang Zhou, Yuying Hu, Baosheng Wang
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110877
影响因子 ：4.800
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PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1(2021/07/26)
作者：Yihui Ma, Peiyi Xia, Zhengyang Wang
期刊：Neoplasia
DOI：doi.org/10.1016/j.neo.2021.07.004
影响因子 ：4.800
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PELI1 overexpression contributes to pancreatic cancer progression through upregulating ubiquitination-mediated INPP5J degradation(2024/04/27)
作者：Wenyang Zhou, Xin Deng, Liling Liu
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111194
影响因子 ：4.800
引用产品：PM150510
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Up-Regulation of SH3TC2 Induced by YTHDF1 Predicts Poor Outcome and Facilitates Cell-Cycle Progress in Colorectal Cancer(2022/12/15)
作者：Huili Wu, Feifei Chu, Lu Li
期刊：Journal of Oncology
影响因子 ：4.501
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Development and Biochemical Characteristics of a monoclonal antibody against prM protein of tembusu virus(2023/08/25)
作者：Siming Zhu, Yi Tang, Youxiang Diao
期刊：POULTRY SCIENCE
影响因子 ：4.400
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Asperuloside regulates the proliferation, apoptosis, and differentiation of chronic myeloid leukemia cell line K562 through the RAS/MEK/ERK pathway(2023/12/16)
作者：Bingjie Zhao, Hong Che, Linlin Li
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e23580
影响因子 ：4.000
引用产品：PM150510
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Roles of the hsa_circ_0013880/USP32/Rap1b axis in the proliferation and apoptosis of acute myeloid leukemia cells: hsa_circ_0013880/USP32/Rap1b in acute myeloid leukemia(2023/03/23)
作者：Heyang Zhang, Yuan Tao, Xin Ding
期刊：ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影响因子 ：3.700
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Ginsenoside Rd Induces Differentiation of Myeloid Leukemia Cells via Regulating ERK/GSK-3β Signaling Pathway(2023/12/12)
作者：Yuxia Jiang, Yanna Zhao, Xiaoling Yu
期刊：Chinese Journal of Integrative Medicine
影响因子 ：2.900
引用产品：PM150510
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