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  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)

SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)

货号:CL-0223

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:Leibovitz's L-1510% FBS1% P/S

数量: - +

  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
  • SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)

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套餐1:

SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确) ¥1600
SW480 [SW-480]细胞专用培养基(L15)
  • ¥350
  • ¥550

现单独购买该产品也可享受限时优惠价!

细胞培养最优解!

套餐组合价:¥1950¥2150

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套餐2:

SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确) ¥1600
SW480 [SW-480]细胞专用培养基(DMEM)
  • ¥350
  • ¥450

现单独购买该产品也可享受限时优惠价!

细胞培养最优解!

套餐组合价:¥1950¥2050

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产品概述
产品信息
名称 SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确)
别称 SW-480; SW 480; SW480E
种属 人类
生长特性 贴壁细胞
细胞形态 上皮细胞样
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养方案A(默认)
生长培养基:
培养条件:
气相:空气,100%, 温度:37℃
培养方案B(可选)
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:2-1:4
推荐换液频率 2-3次/周
注意事项 1. 该细胞推荐使用Leibovitz's L-15培养基进行培养,Leibovitz's L-15不可以通入二氧化碳,会产生细胞毒性; 2. 该细胞不建议更换为DMEM培养,圆形较多,效果不好。
参考资料(来源文献)
背景描述 SW480 [SW-480]细胞源自原位直肠腺癌,和SW620细胞源自同一病人一年后的淋巴结转移。CSAp和直肠抗体3阴性;角蛋白免疫过氧化物酶染色阳性。p53基因第273位密码子的G→A突变引起Arg→His替代,309位密码子的C→T突变导致Pro→Ser替代。细胞p53蛋白表达水平提高,癌基因c-myc、K-ras、H-ras、N-ras、myb、sis和fos的表达呈阳性,癌基因N-myc的表达未做检测。SW480 [SW-480]细胞不表达细胞溶解酶,一种与肿瘤入侵相关的金属蛋白酶。有报道称,SW480 [SW-480]细胞表达GM-CSF。SW480 [SW-480]细胞ras原癌基因的12位密码子有一个突变,可以用作PCR法检测该突变的阳性对照。1978年11月,A·Leibovitz将其提交给ATCC时已传代至第91代。
年龄(性别) 男性;50岁
组织来源 直肠;结直肠腺癌
细胞类型 肿瘤细胞
肿瘤类型 肠癌细胞
生物安全等级 BSL-1
倍增时间 ~30-50 hours
致瘤性 Yes. Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells.
受体表达情况 epidermal growth factor (EGF)
基因表达情况 carcinoembryonic antigen (CEA) 0.7 ng/10^6 cells/10 days; keratin; transforming growth factor beta, myc+; myb+ ; ras+; fos+; sis+; p53+; abl -; ros -; src -, HLA A2, B8, B17; Blood Type A; Rh+, The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes.
保藏机构 ATCC; CCL-228 DSMZ; ACC-313 ECACC; 87092801
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 13,14
    D2S1338 17,24
    D3S1358 15
    D5S818 13
    D7S820 8
    D8S1179 13
    D13S317 12
    D16S539 13
    D18S51 13
    D19S433 13
    D21S11 30,30.2
    FGA 24
    PentaD 9,15
    PentaE 10
    TH01 8
    TPOX 11
    vWA 16
    D6S1043 11,12
    D12S391 17
    D2S441 10,15
  • STR鉴定图
参考文献
文献列表
  • D3S-001, a KRAS G12C inhibitor with rapid target engagement kinetics, overcomes nucleotide cycling and demonstrates robust preclinical and clinical activities(2024/05/08)

    作者:Jing Zhang, Sunmin Lim, Mira Yu

    期刊:Cancer Discovery

    DOI:10.1158/2159-8290.CD-24-0006

    影响因子 :28.200

    引用产品:CL-0223

  • Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGFβ1-mediated tumor progression(2024/04/30)

    作者:Bingjie Guan, Youdong Liu, Bowen Xie

    期刊:Nature Communications

    DOI:10.1038/s41467-024-48100-y

    影响因子 :16.600

    引用产品:CL-0223

  • Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer(2019/06/10)

    作者:Diao He, Zida Ma, Chao Fang

    期刊:Cancer Letters

    DOI:10.1016/j.canlet.2019.04.014

    影响因子 :9.700

    引用产品:CL-0096 CL-0118 CL-0144 CL-0196 CL-0223 CL-0225

  • CHIP-mediated ubiquitination of Galectin-1 predicts colorectal cancer prognosis(2020/01/14)

    作者:Weimin Wang, Zhen Zhou, Liangliang Xiang

    期刊:International Journal of Biological Sciences

    DOI:10.7150/ijbs.41125

    影响因子 :9.200

    引用产品:CL-0096 CL-0223

  • Mitochondrial DNA content reduction induces aerobic glycolysis and reversible resistance to drug-induced apoptosis in SW480 colorectal cancer cells(2018/04/24)

    作者:Jingjing Mou, Jin Peng, Yingying Shi

    期刊:Biomedicine & Pharmacotherapy

    DOI:10.1016/j.biopha.2018.04.099

    影响因子 :7.500

    引用产品:CL-0223

  • Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers(2023/03/10)

    作者:Zehui Zhou, Guizhen Zhou, Chuan Zhou

    期刊:JOURNAL OF MEDICINAL CHEMISTRY

    DOI:10.1021/acs.jmedchem.3c00075

    影响因子 :7.300

    引用产品:CL-0053 CL-0096 CL-0144 CL-0223 CL-0299 CL-0618

  • A 3-circular RNA signature as a noninvasive biomarker for diagnosis of colorectal cancer(2019/11/04)

    作者:Daoxiong Ye, Sisi Wang, Ying Huang

    期刊:Cancer Cell International

    DOI:10.1186/s12935-019-0995-7

    影响因子 :5.800

    引用产品:CL-0096 CL-0223 CL-0225

  • LncRNA-ENST00000543604 exerts a tumor-promoting effect via miRNA 564/AEG-1 or ZNF326/EMT and predicts the prognosis of and chemotherapeutic effect in colorectal cancer.(2022/08/23)

    作者:Weimin Wang, Zhen Zhou, Xiaojun Dai

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2022.960481

    影响因子 :5.738

    引用产品:CL-0223

  • SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway(2024/03/08)

    作者:Bixia Liu, Yang Xie, Jiayu Zhang

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2024.111759

    影响因子 :5.600

    引用产品:CL-0223

  • Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer(2022/01/26)

    作者:Jing Wang, Shaobo Ke, Yi Gong

    期刊:Biomedical Journal

    DOI:10.1016/j.bj.2022.01.007

    影响因子 :5.500

    引用产品:164210 164210-50 CL-0096 CL-0144 CL-0223 CL-0225 PM150110 PM150210

  • Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer organoids(2021/8/15)

    作者:Lisi Zeng, Quanxing Liao, Haoran Zhao

    期刊:Cancer Biology & Medicine

    DOI:10.20892/j.issn.2095-3941.2020.0566

    影响因子 :5.500

    引用产品:CL-0066 CL-0074 CL-0223 CL-0225

  • m6A methyltransferase METTL16 mediates immune evasion of colorectal cancer cells via epigenetically regulating PD-L1 expression(2023/08/29)

    作者:Ailei Wang, Yingjie Sun, Xince Wang

    期刊:Aging-US

    DOI:10.18632/aging.204980

    影响因子 :5.200

    引用产品:CL-0067 CL-0096 CL-0196 CL-0223 CP-H040

  • Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer(2020/01/03)

    作者:Man Hu, Zhaomin Yu, Peiyuan Mei

    期刊:Aging-US

    DOI:10.18632/aging.102606

    影响因子 :5.200

    引用产品:CL-0071 CL-0096 CL-0196 CL-0223

  • Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis(2020/04/30)

    作者:Bing Han, Yang Ge, Junpeng Cui

    期刊:Bioengineered

    DOI:10.1080/21655979.2020.1757224

    影响因子 :4.900

    引用产品:CL-0005 CL-0050 CL-0144 CL-0223 CL-0225 PM150910

  • MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2(2021/10/16)

    作者:Bo Li, Xianyi Liu, Guogang Wu

    期刊:Bioengineered

    DOI:10.1080/21655979.2021.1996505.

    影响因子 :4.900

    引用产品:CL-0096 CL-0118 CL-0144 CL-0223

  • RUNX1-induced upregulation of PTGS2 enhances cell growth, migration and invasion in colorectal cancer cells(2024/05/22)

    作者:Mengchi Chen, Jingfeng Zhang, Hongyuan Huang

    期刊:Scientific Reports

    DOI:10.1038/s41598-024-60296-z

    影响因子 :4.600

    引用产品:CL-0223

  • Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway(2023/12/27)

    作者:Fenglin Luo, Yimeng Tang, Lin Zheng

    期刊:Pharmaceuticals

    DOI:10.3390/ph17010043

    影响因子 :4.600

    引用产品:CL-0223

  • Hsa_circ_0003602 Contributes to the Progression of Colorectal Cancer by Mediating the miR-149-5p/SLC38A1 Axis(2022/09/23)

    作者:Rong Wu, Shiyu Tang, Qiuxiao Wang

    期刊:Gut and Liver

    DOI:10.5009/gnl210542

    影响因子 :4.321

    引用产品:CL-0223

  • Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer(2020/06/28)

    作者:Dingsheng Liu, Hong Zhang, Mingming Cui

    期刊:Cell Cycle

    DOI:10.1080/15384101.2020.1783058

    影响因子 :4.300

    引用产品:CL-0144 CL-0223 PM150910

  • Oct4 promoted proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) in colon cancer cells by activating the SCF/c-Kit signaling pathway(2022/10/18)

    作者:Xiaoqian Bu, Yulong Liu, Lin Wang

    期刊:CELL CYCLE

    DOI:10.1080/15384101.2022.2112486

    影响因子 :4.300

    引用产品:CL-0118 CL-0223

  • Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer(2022/08/02)

    作者:Bo Zhang, Wenbin Cao, Yang Liu

    期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY

    DOI:10.1007/s11010-022-04525-x

    影响因子 :4.300

    引用产品:164210 164210-50 CL-0096 CL-0144 CL-0223 CL-0225 PM150710 PM151010

  • MicroRNA‑129 inhibits colorectal cancer cell proliferation, invasion and epithelial‑to‑mesenchymal transition by targeting SOX4(2021/03/24)

    作者:Zhiping Chen, Tianyu Zhong, Jinghua Zhong

    期刊:Oncol Rep

    DOI:10.3892/or.2021.8012

    影响因子 :4.136

    引用产品:CL-0223 CL-0225

  • Deoxycholic acid-modified microporous SiO2 nanofibers mimicking colorectal microenvironment to optimize radiotherapy-chemotherapy combined therapy(2021/10/12)

    作者:Lihuan Wang, Congzhao Zhao, Haoru Shan

    期刊:Biomedical Materials

    DOI:10.1088/1748-605X/ac2bbb

    影响因子 :4.103

    引用产品:CL-0096 CL-0223

  • miR-145-5p restrained cell growth, invasion, migration and tumorigenesis via modulating RHBDD1 in colorectal cancer via the EGFR-associated signaling pathway(2019/11/03)

    作者:Ying Niu, Jinping Zhang, Yalin Tong

    期刊:International Journal Of Biochemistry & Cell Biology

    DOI:10.1016/j.biocel.2019.105641

    影响因子 :4.000

    引用产品:CL-0050 CL-0074 CL-0144 CL-0223 CL-0229

  • Intestinal metabolite xylulose inhibits colorectal cancer by inducing apoptosis through the MAPK signalling pathway(2024/05/10)

    作者:Qing Hu, Qiao Zheng, Xinhao Du

    期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY

    DOI:10.1016/j.taap.2024.116960

    影响因子 :3.800

    引用产品:CL-0223

  • NSUN6 mediates 5-methylcytosine modification of METTL3 and promotes colon adenocarcinoma progression(2024/05/27)

    作者:Yuanbo Cui, Pengju Lv, Chunyan Zhang

    期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

    DOI:10.1002/jbt.23749

    影响因子 :3.600

    引用产品:CL-0223

  • HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability(2022/09/01)

    作者:Ronglin Wang, Lei Hua, Peixiang Ma

    期刊:NEOPLASMA

    DOI:10.4149/neo_2022_220331N363

    影响因子 :3.409

    引用产品:CL-0223

  • The bromodomain and extra-terminal domain inhibitor JQ1 synergistically sensitizes human colorectal cancer cells to topoisomerase I inhibitors through repression of Mre11-mediated DNA repair pathway(2020/09/26)

    作者:Linping Lei, Xuqin Xie, Long He

    期刊:Investigational New Drugs

    DOI:10.1007/s10637-020-01014-0

    影响因子 :3.400

    引用产品:CL-0096 CL-0118 CL-0144 CL-0196 CL-0223 CL-0225

  • Photodynamic effect of chlorin e6 on cytoskeleton protein of human colon cancer SW480 cells(2021/01/30)

    作者:Haixiu Ma, Kaizhen Yang, Hongxia Li

    期刊:Photodiagnosis and Photodynamic Therapy

    DOI:10.1016/j.pdpdt.2021.102201

    影响因子 :3.300

    引用产品:CL-0223

  • Circ_0029803 serves as the sponge of miR-216b-5p to promote the progression of colorectal cancer by regulating SKIL expression(2021/09/03)

    作者:Linfei Huang , Lei Zhu , Sheng Pan

    期刊:World Journal of Surgical Oncology

    DOI:10.1186/s12957-021-02368-2

    影响因子 :3.200

    引用产品:CL-0096 CL-0223

  • SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway(2019/6/30)

    作者:Xinyue Gu, Yang Jiang, Weinan Xue 

    期刊:Clinical And Experimental Pharmacology And Physiology

    DOI:10.1111/1440-1681.13124

    影响因子 :2.900

    引用产品:CL-0223

  • Naringin Inhibits Colorectal Carcinogenesis by Inhibiting Viability of Colorectal Cancer Cells(2023/06/21)

    作者:Juanni Zeng, Jinyu Tan, Li Mo

    期刊:Chinese Journal of Integrative Medicine

    DOI:10.1007/s11655-023-3698-9

    影响因子 :2.900

    引用产品:CL-0050 CL-0096 CL-0118 CL-0223 PM150411 PM150710 PM151010

  • NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression(2021/9/13)

    作者:Ruikai Li, Chenxiang He, Liangliang Shen

    期刊:Oncology Letters

    DOI:10.3892/ol.2021.13043

    影响因子 :2.900

    引用产品:CL-0005 CL-0223 CL-0225

  • microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16(2021/08/26)

    作者:Wei Li, Zhe Song, Nan Jia

    期刊:In Vitro Cellular & Developmental Biology-Animal

    DOI:10.1007/s11626-021-00603-4

    影响因子 :2.723

    引用产品:CL-0050 CL-0096 CL-0144 CL-0223 CL-0225 PM150710 PM150910 PM151010

  • Development and validation of cuproptosis-related lncRNA signatures for prognosis prediction in colorectal cancer(2023/03/22)

    作者:Lin Pang, Qingqing Wang, Lingxiao Wang

    期刊:BMC Medical Genomics

    DOI:10.1186/s12920-023-01487-x

    影响因子 :2.700

    引用产品:CL-0098 CL-0118 CL-0144 CL-0223 CL-0225

  • circASS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells by regulating the miR‑1269a/VASH1 axis(2021/08/10)

    作者:HaiLin Xiong, XiaoHua Zhong, XiaoHong Guo

    期刊:Experimental and Therapeutic Medicine

    DOI:10.3892/etm.2021.10589

    影响因子 :2.700

    引用产品:CL-0050 CL-0096 CL-0118 CL-0144 CL-0223

  • Identification and characterization of the inhibitory effect of ART on colorectal cancer cells using Raman spectroscopy(2022/01/10)

    作者:Senmao Chai,Xiaodong Sun,Chuhua Fu

    期刊:Journal of Raman Spectroscopy

    DOI:10.1002/jrs.6292

    影响因子 :2.500

    引用产品:CL-0096 CL-0223 CL-0225 PM150710 PM151010

  • Exosomes-derived miR-548am-5p promotes colorectal cancer progression(2023/11/30)

    作者:Fangfang Li, Minglei Zhang, Xiaodong Yin

    期刊:CELLULAR AND MOLECULAR BIOLOGY

    DOI:10.14715/cmb/2023.69.12.17

    影响因子 :1.600

    引用产品:CL-0223

  • The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis(2023/01/11)

    作者:Xingyu Peng, Jinfeng Zhu, Sicheng Liu

    期刊:Journal of Oncology

    DOI:10.1155/2023/4931650

    影响因子 :0.000

    引用产品:CL-0096 CL-0118 CL-0223

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