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产品概述
| 名称 | T-47D (人乳腺管癌细胞) (STR鉴定正确) |
| 别称 | T-47-D; T47-D; T47D:A; T47D |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | T-47细胞分离自一位54岁乳房侵入性导管癌的女性患者胸水；发现分化的上皮亚株(T-47D)有细胞质连接和17-β-雌二醇及其他类固醇降血钙素的受体，T-47D细胞表达WNT7B癌基因。 |
| 年龄（性别） | 女性；54岁 |
| 组织来源 | 乳腺；乳房；导管；来自导管癌肋膜渗出液转移灶 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 乳腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~36-46 hours |
| 致瘤性 | Yes, forms colonies in soft agar. |
| 受体表达情况 | calcitonin, expressed; androgen receptor, expressed; estrogen receptor, expressed; progesterone receptor, expressed; glucocorticoid receptor, positive, expressed; prolactin, expressed; calcitonin; androgen receptor, positive; progesterone receptor, p |
| 保藏机构 | ATCC; HTB-133 DSMZ; ACC-739 ECACC; 85102201 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,13 D2S1338 24 D3S1358 15,17 D5S818 12 D7S820 11 D8S1179 13 D13S317 12 D16S539 10 D18S51 17 D19S433 14 D21S11 28,31 FGA 23 PentaD 10,11,12 PentaE 7,14 TH01 6 TPOX 11 vWA 14 D6S1043 19 D12S391 19 D2S441 14 -
STR鉴定图
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参考文献
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Novel Self-Assembled Multifunctional Nanoprobes for Second-Near-Infrared-Fluorescence-Image-Guided Breast Cancer Surgery and Enhanced Radiotherapy Efficacy(2023/01/31)
作者：Yongqu Zhang, Wanling Liu, Xiangjie Luo
期刊：Advanced Science
影响因子 ：15.100
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Chiral Supramolecular Nanofibers Regulated Tumor-Derived Exosomes Secretion for Constructing an Anti-Tumor Extracellular Microenvironment(2024/02/29)
作者：Beibei Wu, Xiaoqiu Dou, Yu Zhao
期刊：Small
影响因子 ：13.300
引用产品：CL-0228
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Development of a rare earth nanoprobe enables in vivo real-time detection of sentinel lymph node metastasis of breast cancer using NIR-IIb imaging(2023/08/04)
作者：Yuanyuan Zhu, Liang Song, Yongqu Zhang
期刊：CANCER RESEARCH
DOI：10.1158/0008-5472.CAN-22-3432
影响因子 ：11.200
引用产品：CL-0007 CL-0040 CL-0041 CL-0149 CL-0211 CL-0228 CL-0525
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PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis(2023/06/01)
作者：Zhe Wang, Ruolei Li, Niuniu Ho
期刊：Journal for ImmunoTherapy of Cancer
影响因子 ：10.900
引用产品：CL-0007 CL-0041 CL-0093 CL-0149 CL-0211 CL-0228 CL-0525 CM-0007 CM-0041 CM-0093 CM-0149 CM-0211 CM-0228 CM-0525
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Cadmium promotes breast cancer cell proliferation, migration and invasion by inhibiting ACSS2/ATG5-mediated autophagy(2021/01/15)
作者：Yidan Liang, Huifeng Pi, Lingzhi Liao
期刊：Environmental Pollution
DOI：10.1016/j.envpol.2021.116504
影响因子 ：8.900
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Galangin attenuates doxorubicin-induced cardiotoxicity via activating nuclear factor erythroid 2-related factor 2/heme oxygenase 1 signaling pathway to suppress oxidative stress and inflammation(2023/09/01)
作者：Guangyao Fang, Xiuchuan Li, Fengyuan Yang
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7991
影响因子 ：7.200
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N6-methyladenosine-mediated downregulation of miR-374c-5p promotes cadmium-induced cell proliferation and metastasis by targeting GRM3 in breast cancer cells( 2021/12/15)
作者：Yang Yue, Ping Deng, Heng Xiao
期刊： ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2021.113085
影响因子 ：6.800
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Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2(2021/08/16)
作者：Yidan Liang, Lai Yi, Ping Deng
期刊：Ecotoxicology And Environmental Safety
DOI：10.1016/j.ecoenv.2021.112626
影响因子 ：6.800
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A ddPCR platform based on a microfluidic chip with a dual-function flow-focusing structure for sample-to-result DNA quantification analysis(2023/12/28)
作者：xiaoliang zhang, Shun Wang, Jinxian Wang
期刊：LAB ON A CHIP
影响因子 ：6.100
引用产品：CL-0228
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MICAL-L2, as an estrogen-responsive gene, is involved in ER-positive breast cancer cell progression and tamoxifen sensitivity via the AKT/mTOR pathway(2024/05/09)
作者：Pushuai Wen, Jing Li, Zihao Wen
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子 ：5.800
引用产品：CL-0228
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OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer(2023/04/12)
作者：Kexin Wang, Qiuzi Li, Yufeng Fan
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
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Extracellular vesicles released by hypoxia-induced tumor-associated fibroblasts impart chemoresistance to breast cancer cells via long noncoding RNA H19 delivery(2024/01/10)
作者：Shuang Tao, Jian Wang, Fang Li
期刊：FASEB JOURNAL
影响因子 ：4.800
引用产品：CL-0228
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ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway(2023/09/18)
作者：Lu Liu, Wenyue Zhao, Xinyu Zheng
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110892
影响因子 ：4.800
引用产品：CL-0228
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ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop(2023/06/16)
作者：Sijia Han, Xueying Jin, Tianyu Hu
期刊：CARCINOGENESIS
影响因子 ：4.700
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Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling(2024/04/12)
作者：Yun Dong, Gaojian He, Kun Chen
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23724
影响因子 ：4.600
引用产品：CL-0228
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LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway(2023/02/10)
作者：Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi
期刊：ONCOLOGY REPORTS
影响因子 ：4.200
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Selinexor improves the anti-cancer effect of tucidinostat on TP53 wild-type breast cancer(2022/01/13)
作者：Yingfang Shi, Shengxi Xu, Sen Li
期刊：MOLECULAR AND CELLULAR ENDOCRINOLOGY
影响因子 ：4.100
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The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer(2023/09/22)
作者：Yongshuo Yin, Xiao Guan, Genju Li
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2023.116698
影响因子 ：3.800
引用产品：CL-0149 CL-0228 CL-0525 PB180424 PM150110 PM150210 PM150312
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The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway(2022/09/09)
作者：Jiao Yu, Kai Wang, Sanhu Yang
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2022.116232
影响因子 ：3.800
引用产品：CL-0041 CL-0114 CL-0149 CL-0228 CL-0324 CL-0525 PM150110 PM150312 PM150411
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Mutant p53 and ELK1 co-drive FRA-1 Expression to induce metastasis in breast cancer(2023/11/16)
作者：Sike Hu, Manxue Wang, Ailing Ji
期刊：FEBS LETTERS
影响因子 ：3.500
引用产品：CL-0228
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Silence of α1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells(2018/09/27)
作者：Zhijing Zhao, Junfeng Ma, Ying Mao
期刊：Medical Science Monitor
影响因子 ：3.100
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Synthesis of a biocompatible fluorinated multiblock copolymer surfactant for water-in-fluorocarbon droplets and its application in droplet digital polymerase chain reaction(2024/01/09)
作者：Ruijie Feng, Zeqin Li, Junyan Zhu
期刊：JOURNAL OF APPLIED POLYMER SCIENCE
影响因子 ：3.000
引用产品：CL-0228
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Identification of TFR2 as a novel ferroptosis‑related gene that serves an important role in prognosis and progression of triple‑negative breast cancer(2023/12/05)
作者：Yan Yang, Jie Du, Yunfei Huang
期刊：Oncology Letters
影响因子 ：2.900
引用产品：CL-0228
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Kuwanon C inhibits proliferation and induction of apoptosis via the intrinsic pathway in MDA-MB231 and T47D breast cancer cells(2024/05/31)
作者：Peng Qian, Gangxiang Yuan, Chao Yang
期刊：STEROIDS
DOI：10.1016/j.steroids.2024.109450
影响因子 ：2.700
引用产品：CL-0228
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Tumor-Promoting Properties of TMEM9A in Breast Cancer Progression via Activating the Wnt/β-Catenin Signaling Pathway(2023/01/01)
作者：Jianchao He, Yuhui Bu, Xiaolong Li
期刊：BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 ：2.000
引用产品：CL-0228
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![NCI-H1568 [H1568] (人非小细胞肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0690-1.jpg)
